The Lack of Dopamine Transporter Is Associated With Conditional Associative Learning Impairments and Striatal Proteomic Changes

The Lack of Dopamine Transporter Is Associated With Conditional Associative Learning Impairments and Striatal Proteomic Changes

Dopamine (DA) is critically involved in different functions of the central nervous system (CNS) including control of voluntary movement, affect, reward, sleep, and cognition. One of the key components of DA neurotransmission is DA reuptake by the DA transporter (DAT), ensuring rapid clearance of DA...

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Bibliographic Details
Main Authors: Artem Savchenko, Carina Müller, Jana Lubec, Damiana Leo, Volker Korz, Leila Afjehi-Sadat, Jovana Malikovic, Fernando J. Sialana, Gert Lubec, Ilya Sukhanov
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Psychiatry
Subjects:
DAT
proteomic analysis
striatum
associative learning
knock-out animal model
Online Access:https://www.frontiersin.org/articles/10.3389/fpsyt.2022.799433/full

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