Development of RNA aptamers as molecular probes for HER2+ breast cancer study using cell-SELEX

Development of RNA aptamers as molecular probes for HER2+ breast cancer study using cell-SELEX

Objective(s): Development of molecules that specifically recognize cancer cells is one of the major areas in cancer research. Human epidermal growth factor receptor 2 (HER2) is specifically expressed on the surface of breast cancer cells. HER2 is associated with an aggressive phenotype and poor prog...

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Bibliographic Details
Main Authors: Seyedeh Alia Moosavian, Mahmoud Reza Jaafari, Seyed Mohammad Taghdisi, Fatemeh Mosaffa, Ali Badiee, Khalil Abnous
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2015-06-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
Breast cancer
Cell-SELEX
RNA aptamer
TUBO cell line
Online Access:http://ijbms.mums.ac.ir/pdf_4532_d81da845f0f1a0770171012312498abf.html

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