Gender disparities in opioid treatment progress in methadone versus counseling

Abstract Background In the United States, the high dropout rate (75%) in opioid use disorder (OUD) treatment among women and racial/ethnic minorities calls for understanding factors that contribute to making progress in treatment. Whereas counseling and medication for OUD (MOUD, e.g. methadone, bupr...

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Main Authors: Erick Guerrero, Hortensia Amaro, Yinfei Kong, Tenie Khachikian, Jeanne C. Marsh
Format: Article
Language:English
Published: BMC 2021-06-01
Series:Substance Abuse Treatment, Prevention, and Policy
Subjects:
Online Access:https://doi.org/10.1186/s13011-021-00389-4
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author Erick Guerrero
Hortensia Amaro
Yinfei Kong
Tenie Khachikian
Jeanne C. Marsh
author_facet Erick Guerrero
Hortensia Amaro
Yinfei Kong
Tenie Khachikian
Jeanne C. Marsh
author_sort Erick Guerrero
collection DOAJ
description Abstract Background In the United States, the high dropout rate (75%) in opioid use disorder (OUD) treatment among women and racial/ethnic minorities calls for understanding factors that contribute to making progress in treatment. Whereas counseling and medication for OUD (MOUD, e.g. methadone, buprenorphine, naltrexone) is considered the gold standard of care in substance use disorder (SUD) treatment, many individuals with OUD receive either counseling or methadone-only services. This study evaluates gender disparities in treatment plan progress in methadone- compared to counseling-based programs in one of the largest SUD treatment systems in the United States. Methods Multi-year and multi-level (treatment program and client-level) data were analyzed using the Integrated Substance Abuse Treatment to Eliminate Disparities (iSATed) dataset collected in Los Angeles County, California. The sample consisted of 4 waves: 2011 (66 SUD programs, 1035 clients), 2013 (77 SUD programs, 3686 clients), 2015 (75 SUD programs, 4626 clients), and 2017 (69 SUD programs, 4106 clients). We conducted two multi-level negative binomial regressions, one per each outcome (1) making progress towards completing treatment plan, and (2) completing treatment plan. We included outpatient clients discharged on each of the years of the study (over 95% of all clients) and accounted for demographics, wave, homelessness and prior treatment episodes, as well as clients clustered within programs. Results We detected gender differences in two treatment outcomes (progress and completion) considering two outpatient program service types (MOUD-methadone vs. counseling). Clients who received methadone vs. counseling had lower odds of completing their treatment plan (OR = 0.366; 95% CI = 0.163, 0.821). Female clients receiving methadone had lower odds of both making progress (OR = 0.668; 95% CI = 0.481, 0.929) and completing their treatment plan (OR = 0.666; 95% CI = 0.485, 0.916) compared to male clients and receiving counseling. Latina clients had lower odds of completing their treatment plan (OR = 0.617; 95% CI = 0.408, 0.934) compared with non-Latina clients. Conclusions Clients receiving methadone, the most common and highly effective MOUD in reducing opioid use, were less likely to make progress towards or complete their treatment plan than those receiving counseling. Women, and in particular those identified as Latinas, were least likely to benefit from methadone-based programs. These findings have implications for health policy and program design that consider the need for comprehensive and culturally responsive services in methadone-based programs to improve outpatient treatment outcomes among women.
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spelling doaj.art-0efdcf4bb03c497d82ef643f53ac24e22022-12-21T18:51:01ZengBMCSubstance Abuse Treatment, Prevention, and Policy1747-597X2021-06-0116111010.1186/s13011-021-00389-4Gender disparities in opioid treatment progress in methadone versus counselingErick Guerrero0Hortensia Amaro1Yinfei Kong2Tenie Khachikian3Jeanne C. Marsh4I-Lead Institute, Research to End Health Disparities CorpHerbert Wertheim College of Medicine and Robert Stempel College of Public Health and Social Work, Florida International UniversityCollege of Business and Economics, California State University FullertonCrown Family School of Social Work, Policy, and Practice, University of ChicagoCrown Family School of Social Work, Policy, and Practice, University of ChicagoAbstract Background In the United States, the high dropout rate (75%) in opioid use disorder (OUD) treatment among women and racial/ethnic minorities calls for understanding factors that contribute to making progress in treatment. Whereas counseling and medication for OUD (MOUD, e.g. methadone, buprenorphine, naltrexone) is considered the gold standard of care in substance use disorder (SUD) treatment, many individuals with OUD receive either counseling or methadone-only services. This study evaluates gender disparities in treatment plan progress in methadone- compared to counseling-based programs in one of the largest SUD treatment systems in the United States. Methods Multi-year and multi-level (treatment program and client-level) data were analyzed using the Integrated Substance Abuse Treatment to Eliminate Disparities (iSATed) dataset collected in Los Angeles County, California. The sample consisted of 4 waves: 2011 (66 SUD programs, 1035 clients), 2013 (77 SUD programs, 3686 clients), 2015 (75 SUD programs, 4626 clients), and 2017 (69 SUD programs, 4106 clients). We conducted two multi-level negative binomial regressions, one per each outcome (1) making progress towards completing treatment plan, and (2) completing treatment plan. We included outpatient clients discharged on each of the years of the study (over 95% of all clients) and accounted for demographics, wave, homelessness and prior treatment episodes, as well as clients clustered within programs. Results We detected gender differences in two treatment outcomes (progress and completion) considering two outpatient program service types (MOUD-methadone vs. counseling). Clients who received methadone vs. counseling had lower odds of completing their treatment plan (OR = 0.366; 95% CI = 0.163, 0.821). Female clients receiving methadone had lower odds of both making progress (OR = 0.668; 95% CI = 0.481, 0.929) and completing their treatment plan (OR = 0.666; 95% CI = 0.485, 0.916) compared to male clients and receiving counseling. Latina clients had lower odds of completing their treatment plan (OR = 0.617; 95% CI = 0.408, 0.934) compared with non-Latina clients. Conclusions Clients receiving methadone, the most common and highly effective MOUD in reducing opioid use, were less likely to make progress towards or complete their treatment plan than those receiving counseling. Women, and in particular those identified as Latinas, were least likely to benefit from methadone-based programs. These findings have implications for health policy and program design that consider the need for comprehensive and culturally responsive services in methadone-based programs to improve outpatient treatment outcomes among women.https://doi.org/10.1186/s13011-021-00389-4Gender disparitiesTreatment progressOpioid useMOUDCounselingMethadone
spellingShingle Erick Guerrero
Hortensia Amaro
Yinfei Kong
Tenie Khachikian
Jeanne C. Marsh
Gender disparities in opioid treatment progress in methadone versus counseling
Substance Abuse Treatment, Prevention, and Policy
Gender disparities
Treatment progress
Opioid use
MOUD
Counseling
Methadone
title Gender disparities in opioid treatment progress in methadone versus counseling
title_full Gender disparities in opioid treatment progress in methadone versus counseling
title_fullStr Gender disparities in opioid treatment progress in methadone versus counseling
title_full_unstemmed Gender disparities in opioid treatment progress in methadone versus counseling
title_short Gender disparities in opioid treatment progress in methadone versus counseling
title_sort gender disparities in opioid treatment progress in methadone versus counseling
topic Gender disparities
Treatment progress
Opioid use
MOUD
Counseling
Methadone
url https://doi.org/10.1186/s13011-021-00389-4
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AT teniekhachikian genderdisparitiesinopioidtreatmentprogressinmethadoneversuscounseling
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