Antibacterial activity of cinnamon extract against gram-positive and gram-negative bacterial pathogens isolated from patient samples
Background: Medicinal plants have played crucial roles in the traditional health care system since the origin of mankind. Among them, cinnamon is used not only as a spice in food but also as a substance with many health-beneficial effects. The aim of the present study was to identify the antibacteri...
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| Format: | Article |
| Language: | English |
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Golestan University of Medical Sciences
2023-11-01
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| Series: | Medical Laboratory Journal |
| Subjects: | |
| Online Access: | http://mlj.goums.ac.ir/article-1-1671-en.pdf |
| _version_ | 1797220377177358336 |
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| author | Manasa Sireesha Devara Sriushaswini Bhamidipati Vijaya Bharathi Dondapati Narasinga Rao Bandaru |
| author_facet | Manasa Sireesha Devara Sriushaswini Bhamidipati Vijaya Bharathi Dondapati Narasinga Rao Bandaru |
| author_sort | Manasa Sireesha Devara |
| collection | DOAJ |
| description | Background: Medicinal plants have played crucial roles in the traditional health care system since the origin of mankind. Among them, cinnamon is used not only as a spice in food but also as a substance with many health-beneficial effects. The aim of the present study was to identify the antibacterial activity of cinnamon bark extract against bacterial isolates from patient pus samples that might help treat infections.
Methods: The antibacterial potential of cinnamon bark extract in both ethanol and methanol against 6 bacterial isolates obtained from pus samples received in the Microbiology Laboratory was identified by agar well diffusion, minimum inhibitory concentration (MIC), and minimum bactericidal concentration (MBC) using standard techniques.
Results: By agar well diffusion, the highest inhibitory activity of ethanol and methanol extracts of cinnamon was shown by Staphylococcus aureus, followed by coagulase-negative Staphylococci. The lowest inhibitory effect was shown by Proteus mirabilis. The ethanol extract of cinnamon MIC and MBC ranged from 6.25 mg/mL to 12.5 mg/mL and 12.5 mg/mL to 50 mg/mL. The methanol extract of cinnamon MIC showed a value of 12.5 mg/mL, and the methanol extract of MBC ranged from 12.5 mg/mL to 50 mg/mL against all bacterial isolates of the present study.
Conclusion: Staphylococcus aureus is sensitive to the alcoholic extract of cinnamon bark, but its effect is less than that of the selected antibiotic. |
| first_indexed | 2024-04-24T12:48:34Z |
| format | Article |
| id | doaj.art-0f005f0ff73642389f6b59e9a42b81cf |
| institution | Directory Open Access Journal |
| issn | 2538-4449 |
| language | English |
| last_indexed | 2024-04-24T12:48:34Z |
| publishDate | 2023-11-01 |
| publisher | Golestan University of Medical Sciences |
| record_format | Article |
| series | Medical Laboratory Journal |
| spelling | doaj.art-0f005f0ff73642389f6b59e9a42b81cf2024-04-06T09:52:07ZengGolestan University of Medical SciencesMedical Laboratory Journal2538-44492023-11-0117613Antibacterial activity of cinnamon extract against gram-positive and gram-negative bacterial pathogens isolated from patient samplesManasa Sireesha Devara0Sriushaswini Bhamidipati1Vijaya Bharathi Dondapati2Narasinga Rao Bandaru3 Gayatri Vidya Parishad Institute of Health Care and Medical Technology, Visakhapatnam, India Department of Surgery, Gayatri Vidya Parishad Institute of Health Care and Medical Technology, Gvpihcmt, Visakhapatnam, India Department of Microbiology, Gayatri Vidya Parishad Institute of Health care and Medical Technology, Gvpihcmt, Visakhapatnam, India Gayatri Vidya Parishad Institute of Health Care and Medical Technology, Visakhapatnam, India Background: Medicinal plants have played crucial roles in the traditional health care system since the origin of mankind. Among them, cinnamon is used not only as a spice in food but also as a substance with many health-beneficial effects. The aim of the present study was to identify the antibacterial activity of cinnamon bark extract against bacterial isolates from patient pus samples that might help treat infections. Methods: The antibacterial potential of cinnamon bark extract in both ethanol and methanol against 6 bacterial isolates obtained from pus samples received in the Microbiology Laboratory was identified by agar well diffusion, minimum inhibitory concentration (MIC), and minimum bactericidal concentration (MBC) using standard techniques. Results: By agar well diffusion, the highest inhibitory activity of ethanol and methanol extracts of cinnamon was shown by Staphylococcus aureus, followed by coagulase-negative Staphylococci. The lowest inhibitory effect was shown by Proteus mirabilis. The ethanol extract of cinnamon MIC and MBC ranged from 6.25 mg/mL to 12.5 mg/mL and 12.5 mg/mL to 50 mg/mL. The methanol extract of cinnamon MIC showed a value of 12.5 mg/mL, and the methanol extract of MBC ranged from 12.5 mg/mL to 50 mg/mL against all bacterial isolates of the present study. Conclusion: Staphylococcus aureus is sensitive to the alcoholic extract of cinnamon bark, but its effect is less than that of the selected antibiotic.http://mlj.goums.ac.ir/article-1-1671-en.pdfanti-bacterial agentscinnamon oilbarkplant exudates |
| spellingShingle | Manasa Sireesha Devara Sriushaswini Bhamidipati Vijaya Bharathi Dondapati Narasinga Rao Bandaru Antibacterial activity of cinnamon extract against gram-positive and gram-negative bacterial pathogens isolated from patient samples Medical Laboratory Journal anti-bacterial agents cinnamon oil bark plant exudates |
| title | Antibacterial activity of cinnamon extract against gram-positive and gram-negative bacterial
pathogens isolated from patient samples |
| title_full | Antibacterial activity of cinnamon extract against gram-positive and gram-negative bacterial
pathogens isolated from patient samples |
| title_fullStr | Antibacterial activity of cinnamon extract against gram-positive and gram-negative bacterial
pathogens isolated from patient samples |
| title_full_unstemmed | Antibacterial activity of cinnamon extract against gram-positive and gram-negative bacterial
pathogens isolated from patient samples |
| title_short | Antibacterial activity of cinnamon extract against gram-positive and gram-negative bacterial
pathogens isolated from patient samples |
| title_sort | antibacterial activity of cinnamon extract against gram positive and gram negative bacterial pathogens isolated from patient samples |
| topic | anti-bacterial agents cinnamon oil bark plant exudates |
| url | http://mlj.goums.ac.ir/article-1-1671-en.pdf |
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