Expermental research of the effects of benofilin on the functional renal function in the evalution of ethylene glycol toxic loss
Effect of benofilin – a new compound among a new derivative of theophylline and hofitol (70 mg/kg) on functional renal function was studied based on the rat experimental model of acute kidney damage by ethylene glycol. The toxic products of the metabolism of ethylene glycol cause renal tubular damag...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Kazimierz Wielki University
2019-02-01
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| Series: | Journal of Education, Health and Sport |
| Subjects: | |
| Online Access: | https://apcz.umk.pl/JEHS/article/view/25333 |
| _version_ | 1818047695776907264 |
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| author | O. P. Matviychuk A. V. Matviychuk A. V. Taran |
| author_facet | O. P. Matviychuk A. V. Matviychuk A. V. Taran |
| author_sort | O. P. Matviychuk |
| collection | DOAJ |
| description | Effect of benofilin – a new compound among a new derivative of theophylline and hofitol (70 mg/kg) on functional renal function was studied based on the rat experimental model of acute kidney damage by ethylene glycol. The toxic products of the metabolism of ethylene glycol cause renal tubular damage resulting in acute renal failure (ARF). As a result of the application of benofilin its ability is established to prevent the death of animals in the first day of the experiment. By the ability to prevent impaired kidney function in rats benofilin exceeds the effect of the hofitol. |
| first_indexed | 2024-12-10T10:09:53Z |
| format | Article |
| id | doaj.art-0f022d393dbf45a2b4bd25abffec258f |
| institution | Directory Open Access Journal |
| issn | 2391-8306 |
| language | English |
| last_indexed | 2024-12-10T10:09:53Z |
| publishDate | 2019-02-01 |
| publisher | Kazimierz Wielki University |
| record_format | Article |
| series | Journal of Education, Health and Sport |
| spelling | doaj.art-0f022d393dbf45a2b4bd25abffec258f2022-12-22T01:53:08ZengKazimierz Wielki UniversityJournal of Education, Health and Sport2391-83062019-02-0192Expermental research of the effects of benofilin on the functional renal function in the evalution of ethylene glycol toxic lossO. P. Matviychuk0A. V. Matviychuk1A. V. Taran2National University of PharmacyNational University of PharmacyNational University of PharmacyEffect of benofilin – a new compound among a new derivative of theophylline and hofitol (70 mg/kg) on functional renal function was studied based on the rat experimental model of acute kidney damage by ethylene glycol. The toxic products of the metabolism of ethylene glycol cause renal tubular damage resulting in acute renal failure (ARF). As a result of the application of benofilin its ability is established to prevent the death of animals in the first day of the experiment. By the ability to prevent impaired kidney function in rats benofilin exceeds the effect of the hofitol.https://apcz.umk.pl/JEHS/article/view/25333benofilinacute kidney damagediureticnephroprotective activityrats |
| spellingShingle | O. P. Matviychuk A. V. Matviychuk A. V. Taran Expermental research of the effects of benofilin on the functional renal function in the evalution of ethylene glycol toxic loss Journal of Education, Health and Sport benofilin acute kidney damage diuretic nephroprotective activity rats |
| title | Expermental research of the effects of benofilin on the functional renal function in the evalution of ethylene glycol toxic loss |
| title_full | Expermental research of the effects of benofilin on the functional renal function in the evalution of ethylene glycol toxic loss |
| title_fullStr | Expermental research of the effects of benofilin on the functional renal function in the evalution of ethylene glycol toxic loss |
| title_full_unstemmed | Expermental research of the effects of benofilin on the functional renal function in the evalution of ethylene glycol toxic loss |
| title_short | Expermental research of the effects of benofilin on the functional renal function in the evalution of ethylene glycol toxic loss |
| title_sort | expermental research of the effects of benofilin on the functional renal function in the evalution of ethylene glycol toxic loss |
| topic | benofilin acute kidney damage diuretic nephroprotective activity rats |
| url | https://apcz.umk.pl/JEHS/article/view/25333 |
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