Pseudocapsule and pseudocapsule-based extracapsular resection in pituitary neuroendocrine tumors
Since Costello et al. proposed the concept of pseudocapsule of pituitary neuroendocrine tumors (PitNETs) in 1936, many studies have been published on its occurrence, development process, histopathology, and morphology. Pseudocapsule has been proposed as the anatomical interface between PitNETs and n...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-11-01
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| Series: | Frontiers in Endocrinology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fendo.2022.1056327/full |
| _version_ | 1811189651445121024 |
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| author | Xiao Bin Wang Tian Yi Han Jian Gong Ma Cheng He Li Xue Xun Zhang Zhe Bao Wu |
| author_facet | Xiao Bin Wang Tian Yi Han Jian Gong Ma Cheng He Li Xue Xun Zhang Zhe Bao Wu |
| author_sort | Xiao Bin Wang |
| collection | DOAJ |
| description | Since Costello et al. proposed the concept of pseudocapsule of pituitary neuroendocrine tumors (PitNETs) in 1936, many studies have been published on its occurrence, development process, histopathology, and morphology. Pseudocapsule has been proposed as the anatomical interface between PitNETs and normal pituitary gland, therefore the so-called pseudocapsule-based extracapsular resection (ER) technique was developed as an extracapsular surgery method for PitNETs,which differs from the conventional intracapsular resection (IR). In recent years, ER has also been widely used in patients of different tumor types, sizes, and age groups, because the pseudocapsule can be identified more clearly under the endoscopy. Endoscopic transsphenoidal resection for PitNETs has become the preferred surgical method. We reviewed relevant literatures in the past 10 years, showing that ER could achieve better rate of gross total resection (GTR) and biochemical remission, and reduce tumor recurrence than IR, without increasing postoperative complications. Therefore, the pseudocapsule and ER should be valued by neurosurgeons and actively promoted clinically. |
| first_indexed | 2024-04-11T14:38:06Z |
| format | Article |
| id | doaj.art-0f02d6861b724418b1cd3a12ae585153 |
| institution | Directory Open Access Journal |
| issn | 1664-2392 |
| language | English |
| last_indexed | 2024-04-11T14:38:06Z |
| publishDate | 2022-11-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Endocrinology |
| spelling | doaj.art-0f02d6861b724418b1cd3a12ae5851532022-12-22T04:18:13ZengFrontiers Media S.A.Frontiers in Endocrinology1664-23922022-11-011310.3389/fendo.2022.10563271056327Pseudocapsule and pseudocapsule-based extracapsular resection in pituitary neuroendocrine tumorsXiao Bin Wang0Tian Yi Han1Jian Gong Ma2Cheng He3Li Xue4Xun Zhang5Zhe Bao Wu6Department Of Neurosurgery, The First Affiliated Hospital of Henan University, Kaifeng, Henan, ChinaDepartment Of Neurosurgery, Center of Pituitary Tumors, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, ChinaDepartment Of Neurosurgery, The First Affiliated Hospital of Henan University, Kaifeng, Henan, ChinaDepartment Of Neurosurgery, The First Affiliated Hospital of Henan University, Kaifeng, Henan, ChinaDepartment Of Neurosurgery, Center of Pituitary Tumors, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, ChinaNeuroendocrine Research Laboratory, Massachusetts General Hospital and Harvard Medical School, Boston, MA, United StatesDepartment Of Neurosurgery, Center of Pituitary Tumors, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, ChinaSince Costello et al. proposed the concept of pseudocapsule of pituitary neuroendocrine tumors (PitNETs) in 1936, many studies have been published on its occurrence, development process, histopathology, and morphology. Pseudocapsule has been proposed as the anatomical interface between PitNETs and normal pituitary gland, therefore the so-called pseudocapsule-based extracapsular resection (ER) technique was developed as an extracapsular surgery method for PitNETs,which differs from the conventional intracapsular resection (IR). In recent years, ER has also been widely used in patients of different tumor types, sizes, and age groups, because the pseudocapsule can be identified more clearly under the endoscopy. Endoscopic transsphenoidal resection for PitNETs has become the preferred surgical method. We reviewed relevant literatures in the past 10 years, showing that ER could achieve better rate of gross total resection (GTR) and biochemical remission, and reduce tumor recurrence than IR, without increasing postoperative complications. Therefore, the pseudocapsule and ER should be valued by neurosurgeons and actively promoted clinically.https://www.frontiersin.org/articles/10.3389/fendo.2022.1056327/fullpituitary neuroendocrine tumorspseudocapsulepseudocapsule-based extracapsular resectionintracapsular resectionneuroendoscopy |
| spellingShingle | Xiao Bin Wang Tian Yi Han Jian Gong Ma Cheng He Li Xue Xun Zhang Zhe Bao Wu Pseudocapsule and pseudocapsule-based extracapsular resection in pituitary neuroendocrine tumors Frontiers in Endocrinology pituitary neuroendocrine tumors pseudocapsule pseudocapsule-based extracapsular resection intracapsular resection neuroendoscopy |
| title | Pseudocapsule and pseudocapsule-based extracapsular resection in pituitary neuroendocrine tumors |
| title_full | Pseudocapsule and pseudocapsule-based extracapsular resection in pituitary neuroendocrine tumors |
| title_fullStr | Pseudocapsule and pseudocapsule-based extracapsular resection in pituitary neuroendocrine tumors |
| title_full_unstemmed | Pseudocapsule and pseudocapsule-based extracapsular resection in pituitary neuroendocrine tumors |
| title_short | Pseudocapsule and pseudocapsule-based extracapsular resection in pituitary neuroendocrine tumors |
| title_sort | pseudocapsule and pseudocapsule based extracapsular resection in pituitary neuroendocrine tumors |
| topic | pituitary neuroendocrine tumors pseudocapsule pseudocapsule-based extracapsular resection intracapsular resection neuroendoscopy |
| url | https://www.frontiersin.org/articles/10.3389/fendo.2022.1056327/full |
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