Posttraumatic stress disorder: from diagnosis to prevention
Abstract Posttraumatic stress disorder (PTSD) is a chronic impairment disorder that occurs after exposure to traumatic events. This disorder can result in a disturbance to individual and family functioning, causing significant medical, financial, and social problems. This study is a selective review...
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Format: | Article |
Language: | English |
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BMC
2018-09-01
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Series: | Military Medical Research |
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Online Access: | http://link.springer.com/article/10.1186/s40779-018-0179-0 |
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author | Xue-Rong Miao Qian-Bo Chen Kai Wei Kun-Ming Tao Zhi-Jie Lu |
author_facet | Xue-Rong Miao Qian-Bo Chen Kai Wei Kun-Ming Tao Zhi-Jie Lu |
author_sort | Xue-Rong Miao |
collection | DOAJ |
description | Abstract Posttraumatic stress disorder (PTSD) is a chronic impairment disorder that occurs after exposure to traumatic events. This disorder can result in a disturbance to individual and family functioning, causing significant medical, financial, and social problems. This study is a selective review of literature aiming to provide a general outlook of the current understanding of PTSD. There are several diagnostic guidelines for PTSD, with the most recent editions of the DSM-5 and ICD-11 being best accepted. Generally, PTSD is diagnosed according to several clusters of symptoms occurring after exposure to extreme stressors. Its pathogenesis is multifactorial, including the activation of the hypothalamic–pituitary–adrenal (HPA) axis, immune response, or even genetic discrepancy. The morphological alternation of subcortical brain structures may also correlate with PTSD symptoms. Prevention and treatment methods for PTSD vary from psychological interventions to pharmacological medications. Overall, the findings of pertinent studies are difficult to generalize because of heterogeneous patient groups, different traumatic events, diagnostic criteria, and study designs. Future investigations are needed to determine which guideline or inspection method is the best for early diagnosis and which strategies might prevent the development of PTSD. |
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format | Article |
id | doaj.art-0f06c36105e04b8c9d6cb8818e0582ac |
institution | Directory Open Access Journal |
issn | 2054-9369 |
language | English |
last_indexed | 2024-12-20T18:45:39Z |
publishDate | 2018-09-01 |
publisher | BMC |
record_format | Article |
series | Military Medical Research |
spelling | doaj.art-0f06c36105e04b8c9d6cb8818e0582ac2022-12-21T19:29:43ZengBMCMilitary Medical Research2054-93692018-09-01511710.1186/s40779-018-0179-0Posttraumatic stress disorder: from diagnosis to preventionXue-Rong Miao0Qian-Bo Chen1Kai Wei2Kun-Ming Tao3Zhi-Jie Lu4Department of Anesthesiology and Intensive Care, Third Affiliated Hospital of Second Military Medical UniversityDepartment of Anesthesiology and Intensive Care, Third Affiliated Hospital of Second Military Medical UniversityDepartment of Anesthesiology and Intensive Care, Third Affiliated Hospital of Second Military Medical UniversityDepartment of Anesthesiology and Intensive Care, Third Affiliated Hospital of Second Military Medical UniversityDepartment of Anesthesiology and Intensive Care, Third Affiliated Hospital of Second Military Medical UniversityAbstract Posttraumatic stress disorder (PTSD) is a chronic impairment disorder that occurs after exposure to traumatic events. This disorder can result in a disturbance to individual and family functioning, causing significant medical, financial, and social problems. This study is a selective review of literature aiming to provide a general outlook of the current understanding of PTSD. There are several diagnostic guidelines for PTSD, with the most recent editions of the DSM-5 and ICD-11 being best accepted. Generally, PTSD is diagnosed according to several clusters of symptoms occurring after exposure to extreme stressors. Its pathogenesis is multifactorial, including the activation of the hypothalamic–pituitary–adrenal (HPA) axis, immune response, or even genetic discrepancy. The morphological alternation of subcortical brain structures may also correlate with PTSD symptoms. Prevention and treatment methods for PTSD vary from psychological interventions to pharmacological medications. Overall, the findings of pertinent studies are difficult to generalize because of heterogeneous patient groups, different traumatic events, diagnostic criteria, and study designs. Future investigations are needed to determine which guideline or inspection method is the best for early diagnosis and which strategies might prevent the development of PTSD.http://link.springer.com/article/10.1186/s40779-018-0179-0PTSDStressCognitive impairmentPsychological interventionsNeuroendocrine |
spellingShingle | Xue-Rong Miao Qian-Bo Chen Kai Wei Kun-Ming Tao Zhi-Jie Lu Posttraumatic stress disorder: from diagnosis to prevention Military Medical Research PTSD Stress Cognitive impairment Psychological interventions Neuroendocrine |
title | Posttraumatic stress disorder: from diagnosis to prevention |
title_full | Posttraumatic stress disorder: from diagnosis to prevention |
title_fullStr | Posttraumatic stress disorder: from diagnosis to prevention |
title_full_unstemmed | Posttraumatic stress disorder: from diagnosis to prevention |
title_short | Posttraumatic stress disorder: from diagnosis to prevention |
title_sort | posttraumatic stress disorder from diagnosis to prevention |
topic | PTSD Stress Cognitive impairment Psychological interventions Neuroendocrine |
url | http://link.springer.com/article/10.1186/s40779-018-0179-0 |
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