Posttraumatic stress disorder: from diagnosis to prevention

Abstract Posttraumatic stress disorder (PTSD) is a chronic impairment disorder that occurs after exposure to traumatic events. This disorder can result in a disturbance to individual and family functioning, causing significant medical, financial, and social problems. This study is a selective review...

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Main Authors: Xue-Rong Miao, Qian-Bo Chen, Kai Wei, Kun-Ming Tao, Zhi-Jie Lu
Format: Article
Language:English
Published: BMC 2018-09-01
Series:Military Medical Research
Subjects:
Online Access:http://link.springer.com/article/10.1186/s40779-018-0179-0
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author Xue-Rong Miao
Qian-Bo Chen
Kai Wei
Kun-Ming Tao
Zhi-Jie Lu
author_facet Xue-Rong Miao
Qian-Bo Chen
Kai Wei
Kun-Ming Tao
Zhi-Jie Lu
author_sort Xue-Rong Miao
collection DOAJ
description Abstract Posttraumatic stress disorder (PTSD) is a chronic impairment disorder that occurs after exposure to traumatic events. This disorder can result in a disturbance to individual and family functioning, causing significant medical, financial, and social problems. This study is a selective review of literature aiming to provide a general outlook of the current understanding of PTSD. There are several diagnostic guidelines for PTSD, with the most recent editions of the DSM-5 and ICD-11 being best accepted. Generally, PTSD is diagnosed according to several clusters of symptoms occurring after exposure to extreme stressors. Its pathogenesis is multifactorial, including the activation of the hypothalamic–pituitary–adrenal (HPA) axis, immune response, or even genetic discrepancy. The morphological alternation of subcortical brain structures may also correlate with PTSD symptoms. Prevention and treatment methods for PTSD vary from psychological interventions to pharmacological medications. Overall, the findings of pertinent studies are difficult to generalize because of heterogeneous patient groups, different traumatic events, diagnostic criteria, and study designs. Future investigations are needed to determine which guideline or inspection method is the best for early diagnosis and which strategies might prevent the development of PTSD.
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spelling doaj.art-0f06c36105e04b8c9d6cb8818e0582ac2022-12-21T19:29:43ZengBMCMilitary Medical Research2054-93692018-09-01511710.1186/s40779-018-0179-0Posttraumatic stress disorder: from diagnosis to preventionXue-Rong Miao0Qian-Bo Chen1Kai Wei2Kun-Ming Tao3Zhi-Jie Lu4Department of Anesthesiology and Intensive Care, Third Affiliated Hospital of Second Military Medical UniversityDepartment of Anesthesiology and Intensive Care, Third Affiliated Hospital of Second Military Medical UniversityDepartment of Anesthesiology and Intensive Care, Third Affiliated Hospital of Second Military Medical UniversityDepartment of Anesthesiology and Intensive Care, Third Affiliated Hospital of Second Military Medical UniversityDepartment of Anesthesiology and Intensive Care, Third Affiliated Hospital of Second Military Medical UniversityAbstract Posttraumatic stress disorder (PTSD) is a chronic impairment disorder that occurs after exposure to traumatic events. This disorder can result in a disturbance to individual and family functioning, causing significant medical, financial, and social problems. This study is a selective review of literature aiming to provide a general outlook of the current understanding of PTSD. There are several diagnostic guidelines for PTSD, with the most recent editions of the DSM-5 and ICD-11 being best accepted. Generally, PTSD is diagnosed according to several clusters of symptoms occurring after exposure to extreme stressors. Its pathogenesis is multifactorial, including the activation of the hypothalamic–pituitary–adrenal (HPA) axis, immune response, or even genetic discrepancy. The morphological alternation of subcortical brain structures may also correlate with PTSD symptoms. Prevention and treatment methods for PTSD vary from psychological interventions to pharmacological medications. Overall, the findings of pertinent studies are difficult to generalize because of heterogeneous patient groups, different traumatic events, diagnostic criteria, and study designs. Future investigations are needed to determine which guideline or inspection method is the best for early diagnosis and which strategies might prevent the development of PTSD.http://link.springer.com/article/10.1186/s40779-018-0179-0PTSDStressCognitive impairmentPsychological interventionsNeuroendocrine
spellingShingle Xue-Rong Miao
Qian-Bo Chen
Kai Wei
Kun-Ming Tao
Zhi-Jie Lu
Posttraumatic stress disorder: from diagnosis to prevention
Military Medical Research
PTSD
Stress
Cognitive impairment
Psychological interventions
Neuroendocrine
title Posttraumatic stress disorder: from diagnosis to prevention
title_full Posttraumatic stress disorder: from diagnosis to prevention
title_fullStr Posttraumatic stress disorder: from diagnosis to prevention
title_full_unstemmed Posttraumatic stress disorder: from diagnosis to prevention
title_short Posttraumatic stress disorder: from diagnosis to prevention
title_sort posttraumatic stress disorder from diagnosis to prevention
topic PTSD
Stress
Cognitive impairment
Psychological interventions
Neuroendocrine
url http://link.springer.com/article/10.1186/s40779-018-0179-0
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AT kaiwei posttraumaticstressdisorderfromdiagnosistoprevention
AT kunmingtao posttraumaticstressdisorderfromdiagnosistoprevention
AT zhijielu posttraumaticstressdisorderfromdiagnosistoprevention