DNA origami-enhanced binding of aptamers to Staphylococcus aureus cells

DNA origami-enhanced binding of aptamers to Staphylococcus aureus cells

The combination of DNA origami nanostructures and aptamers provides a powerful technology for diagnostic assays. Here, we functionalized a DNA origami nanostructure with a Protein-A binding aptamer to target Staphylococcus aureus bacterial cells. Using an enzyme-linked oligonucleotide assay (ELONA),...

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Bibliographic Details
Main Authors: Yasaman Ahmadi, Trishant R. Umrekar, Natalie Mutter, Morgan Beeby, Ivan Barišić
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:Biosensors and Bioelectronics: X
Subjects:
DNA origami
Aptamers
Diagnostic assay
Pathogens
Online Access:http://www.sciencedirect.com/science/article/pii/S2590137023001395

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