Melatonin Promotes In Vitro Maturation of Vitrified-Warmed Mouse Germinal Vesicle Oocytes, Potentially by Reducing Oxidative Stress through the Nrf2 Pathway

Melatonin Promotes In Vitro Maturation of Vitrified-Warmed Mouse Germinal Vesicle Oocytes, Potentially by Reducing Oxidative Stress through the Nrf2 Pathway

Previously it was reported that melatonin could mitigate oxidative stress caused by oocyte cryopreservation; however, the underlying molecular mechanisms which cause this remain unclear. The objective was to explore whether melatonin could reduce oxidative stress during in vitro maturation of vitrif...

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Bibliographic Details
Main Authors: Shichao Guo, Jinyu Yang, Jianpeng Qin, Izhar Hyder Qazi, Bo Pan, Shengqin Zang, Tianyi Lv, Shoulong Deng, Yi Fang, Guangbin Zhou
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Animals
Subjects:
vitrification
receptors
antioxidants
reactive oxygen species
Nrf2
Online Access:https://www.mdpi.com/2076-2615/11/8/2324

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