Metabolomic Analysis of Small Extracellular Vesicles Derived from Pancreatic Cancer Cells Cultured under Normoxia and Hypoxia

Metabolomic Analysis of Small Extracellular Vesicles Derived from Pancreatic Cancer Cells Cultured under Normoxia and Hypoxia

Extracellular vesicles (EVs) released from cancer cells contribute to various malignant phenotypes of cancer, including metastasis, cachexia, and angiogenesis. Although DNA, mRNAs, miRNAs, and proteins contained in EVs have been extensively studied, the function of metabolites in EVs remains unclear...

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Bibliographic Details
Main Authors:	Ryosuke Hayasaka, Sho Tabata, Masako Hasebe, Satsuki Ikeda, Sumiko Ohnuma, Masaru Mori, Tomoyoshi Soga, Masaru Tomita, Akiyoshi Hirayama
Format:	Article
Language:	English
Published:	MDPI AG 2021-04-01
Series:	Metabolites
Subjects:	small extracellular vesicles metabolome analysis pancreatic cancer hypoxia capillary ion chromatography-mass spectrometry liquid chromatography-mass spectrometry
Online Access:	https://www.mdpi.com/2218-1989/11/4/215

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