A 5-year evaluation of early-and late-onset sporadic colorectal cancer screening in central Saudi Arabia
Background: The Al-Kharj colorectal cancer (CRC) screening program was implemented for five years (2017-2022) in a central urban area of Riyadh Province, Saudi Arabia, to assess the participation and impact of the program in average-risk individuals. Methods: The high sensitivity-guaiac based-fecal...
| Main Authors: | , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2023-01-01
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| Series: | The Saudi Journal of Gastroenterology |
| Subjects: | |
| Online Access: | http://www.saudijgastro.com/article.asp?issn=1319-3767;year=2023;volume=29;issue=2;spage=95;epage=101;aulast=Zacharakis |
| _version_ | 1797775333212028928 |
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| author | Georgios Zacharakis Abdulaziz Almasoud Omar Arahmaner Khaled Aldossary Jamaan Alzahrani Sameer Al-Ghamdi Abdullah AlShehri Pavlos Nikolaidis Abdullah Bawazir Talal Alfayez Moataz Daadour Faisal Alslimah Mohammed Altamimi Sami Alshalawi |
| author_facet | Georgios Zacharakis Abdulaziz Almasoud Omar Arahmaner Khaled Aldossary Jamaan Alzahrani Sameer Al-Ghamdi Abdullah AlShehri Pavlos Nikolaidis Abdullah Bawazir Talal Alfayez Moataz Daadour Faisal Alslimah Mohammed Altamimi Sami Alshalawi |
| author_sort | Georgios Zacharakis |
| collection | DOAJ |
| description | Background: The Al-Kharj colorectal cancer (CRC) screening program was implemented for five years (2017-2022) in a central urban area of Riyadh Province, Saudi Arabia, to assess the participation and impact of the program in average-risk individuals.
Methods: The high sensitivity-guaiac based-fecal occult blood test (HSgFOBT) was used as a first-line investigation to identify asymptomatic patients, aged 45–75 years, requiring CRC screening using colonoscopy. The program was run in three tertiary hospitals in the area.
Results: The five-year participation rate was 73% (35,640/48,897). The average age was 53 years (range 45–75), 49% were female (17,464/35,640), all were asymptomatic, and 77% had adequate bowel preparation. The HSgFOBT (+) rate was 6.3% (n = 2245), and 76% (n = 1701) of these underwent colonoscopy. The prevalence of findings were as follows: CRC, 4.8% (81/1701); advanced adenoma, 9.5% (162/1701); adenoma, 15.9% (270/1701); non-adenomatous polyps, 7.9% (135/1701); and no polyps or tumors, 25.4% (432/1701). Among participants aged 45–50 years, early onset-CRC had female predominance, while those ≥50 years with late onset-CRC were predominantly male. CRC was more prevalent in the left colon (P < 0.005).
Conclusions: Approximately one-third of the participants diagnosed with CRC had early-onset CRC. Screening participation was desirable for the defined target population. Public education is necessary along with expanded colonoscopy resources to continue further citizen participation. |
| first_indexed | 2024-03-12T22:34:11Z |
| format | Article |
| id | doaj.art-0f11a7b8433d4d61b3249503f6a07d1d |
| institution | Directory Open Access Journal |
| issn | 1319-3767 1998-4049 |
| language | English |
| last_indexed | 2024-03-12T22:34:11Z |
| publishDate | 2023-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | The Saudi Journal of Gastroenterology |
| spelling | doaj.art-0f11a7b8433d4d61b3249503f6a07d1d2023-07-21T13:05:03ZengWolters Kluwer Medknow PublicationsThe Saudi Journal of Gastroenterology1319-37671998-40492023-01-012929510110.4103/sjg.sjg_333_22A 5-year evaluation of early-and late-onset sporadic colorectal cancer screening in central Saudi ArabiaGeorgios ZacharakisAbdulaziz AlmasoudOmar ArahmanerKhaled AldossaryJamaan AlzahraniSameer Al-GhamdiAbdullah AlShehriPavlos NikolaidisAbdullah BawazirTalal AlfayezMoataz DaadourFaisal AlslimahMohammed AltamimiSami AlshalawiBackground: The Al-Kharj colorectal cancer (CRC) screening program was implemented for five years (2017-2022) in a central urban area of Riyadh Province, Saudi Arabia, to assess the participation and impact of the program in average-risk individuals. Methods: The high sensitivity-guaiac based-fecal occult blood test (HSgFOBT) was used as a first-line investigation to identify asymptomatic patients, aged 45–75 years, requiring CRC screening using colonoscopy. The program was run in three tertiary hospitals in the area. Results: The five-year participation rate was 73% (35,640/48,897). The average age was 53 years (range 45–75), 49% were female (17,464/35,640), all were asymptomatic, and 77% had adequate bowel preparation. The HSgFOBT (+) rate was 6.3% (n = 2245), and 76% (n = 1701) of these underwent colonoscopy. The prevalence of findings were as follows: CRC, 4.8% (81/1701); advanced adenoma, 9.5% (162/1701); adenoma, 15.9% (270/1701); non-adenomatous polyps, 7.9% (135/1701); and no polyps or tumors, 25.4% (432/1701). Among participants aged 45–50 years, early onset-CRC had female predominance, while those ≥50 years with late onset-CRC were predominantly male. CRC was more prevalent in the left colon (P < 0.005). Conclusions: Approximately one-third of the participants diagnosed with CRC had early-onset CRC. Screening participation was desirable for the defined target population. Public education is necessary along with expanded colonoscopy resources to continue further citizen participation.http://www.saudijgastro.com/article.asp?issn=1319-3767;year=2023;volume=29;issue=2;spage=95;epage=101;aulast=Zacharakisadvanced adenomascolonoscopycolorectal cancer screeningearly onset |
| spellingShingle | Georgios Zacharakis Abdulaziz Almasoud Omar Arahmaner Khaled Aldossary Jamaan Alzahrani Sameer Al-Ghamdi Abdullah AlShehri Pavlos Nikolaidis Abdullah Bawazir Talal Alfayez Moataz Daadour Faisal Alslimah Mohammed Altamimi Sami Alshalawi A 5-year evaluation of early-and late-onset sporadic colorectal cancer screening in central Saudi Arabia The Saudi Journal of Gastroenterology advanced adenomas colonoscopy colorectal cancer screening early onset |
| title | A 5-year evaluation of early-and late-onset sporadic colorectal cancer screening in central Saudi Arabia |
| title_full | A 5-year evaluation of early-and late-onset sporadic colorectal cancer screening in central Saudi Arabia |
| title_fullStr | A 5-year evaluation of early-and late-onset sporadic colorectal cancer screening in central Saudi Arabia |
| title_full_unstemmed | A 5-year evaluation of early-and late-onset sporadic colorectal cancer screening in central Saudi Arabia |
| title_short | A 5-year evaluation of early-and late-onset sporadic colorectal cancer screening in central Saudi Arabia |
| title_sort | 5 year evaluation of early and late onset sporadic colorectal cancer screening in central saudi arabia |
| topic | advanced adenomas colonoscopy colorectal cancer screening early onset |
| url | http://www.saudijgastro.com/article.asp?issn=1319-3767;year=2023;volume=29;issue=2;spage=95;epage=101;aulast=Zacharakis |
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