Scientific Opinion on re‐evaluation of chlorophyllins (E 140(ii)) as food additives
Abstract Chlorophyllins (E 140(i)) are obtained by saponification of a solvent extract from sources, such as grass, lucerne, and nettle, that could not be regarded as edible plant material or food for humans. Chlorophyllins represent 90 % of the colouring matter in the food additive E 140(ii); the r...
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| Format: | Article |
| Language: | English |
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Wiley
2015-05-01
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| Series: | EFSA Journal |
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| Online Access: | https://doi.org/10.2903/j.efsa.2015.4085 |
| _version_ | 1823939360230211584 |
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| author | EFSA Panel on Food Additives and Nutrient Sources added to Food (ANS) |
| author_facet | EFSA Panel on Food Additives and Nutrient Sources added to Food (ANS) |
| author_sort | EFSA Panel on Food Additives and Nutrient Sources added to Food (ANS) |
| collection | DOAJ |
| description | Abstract Chlorophyllins (E 140(i)) are obtained by saponification of a solvent extract from sources, such as grass, lucerne, and nettle, that could not be regarded as edible plant material or food for humans. Chlorophyllins represent 90 % of the colouring matter in the food additive E 140(ii); the remaining part consists of other pigments, such as carotenoids, together with oils, fats and waxes derived from the source material. The Panel noted that the material used in many studies, identified as “chlorophyllins”, was quite often, if not always, a copper complex of chlorophyllins (E 141(ii)). There are no data regarding the absorption, distribution, metabolism and excretion (ADME) and toxicity of chlorophyllins (E 140(ii)). Considering the available data on chlorophylls (E 140(i)), the Panel concluded that chlorophyllins are not metabolites of chlorophylls in humans and owing to their differences in physico‐chemical properties, it was not possible to support read‐across for toxicity data between these two compounds. The Panel considered that it is necessary to carefully review the definition and identity of E 140(ii) in order to adequately characterise the food additive E 140(ii)) as used in the market. This will also allow proper assessment of its safety when relevant studies of the compound to which consumers are actually exposed become available. Considering the absence of relevant ADME and toxicity data, and because chlorophyllins (E 140(ii)) are neither natural constituents of the regular diet nor metabolites of chlorophylls in humans, the Panel concluded that it was not possible to assess the safety of chlorophyllins (E 140(ii)) as food additives. |
| first_indexed | 2024-12-17T02:57:15Z |
| format | Article |
| id | doaj.art-0f14ed87ae6d4d69aad035483b9adf76 |
| institution | Directory Open Access Journal |
| issn | 1831-4732 |
| language | English |
| last_indexed | 2024-12-17T02:57:15Z |
| publishDate | 2015-05-01 |
| publisher | Wiley |
| record_format | Article |
| series | EFSA Journal |
| spelling | doaj.art-0f14ed87ae6d4d69aad035483b9adf762022-12-21T22:06:13ZengWileyEFSA Journal1831-47322015-05-01135n/an/a10.2903/j.efsa.2015.4085Scientific Opinion on re‐evaluation of chlorophyllins (E 140(ii)) as food additivesEFSA Panel on Food Additives and Nutrient Sources added to Food (ANS)Abstract Chlorophyllins (E 140(i)) are obtained by saponification of a solvent extract from sources, such as grass, lucerne, and nettle, that could not be regarded as edible plant material or food for humans. Chlorophyllins represent 90 % of the colouring matter in the food additive E 140(ii); the remaining part consists of other pigments, such as carotenoids, together with oils, fats and waxes derived from the source material. The Panel noted that the material used in many studies, identified as “chlorophyllins”, was quite often, if not always, a copper complex of chlorophyllins (E 141(ii)). There are no data regarding the absorption, distribution, metabolism and excretion (ADME) and toxicity of chlorophyllins (E 140(ii)). Considering the available data on chlorophylls (E 140(i)), the Panel concluded that chlorophyllins are not metabolites of chlorophylls in humans and owing to their differences in physico‐chemical properties, it was not possible to support read‐across for toxicity data between these two compounds. The Panel considered that it is necessary to carefully review the definition and identity of E 140(ii) in order to adequately characterise the food additive E 140(ii)) as used in the market. This will also allow proper assessment of its safety when relevant studies of the compound to which consumers are actually exposed become available. Considering the absence of relevant ADME and toxicity data, and because chlorophyllins (E 140(ii)) are neither natural constituents of the regular diet nor metabolites of chlorophylls in humans, the Panel concluded that it was not possible to assess the safety of chlorophyllins (E 140(ii)) as food additives.https://doi.org/10.2903/j.efsa.2015.4085Chlorophyllinschlorophyllin achlorophyllin bchlorin e6rhodin g7E 140(ii) |
| spellingShingle | EFSA Panel on Food Additives and Nutrient Sources added to Food (ANS) Scientific Opinion on re‐evaluation of chlorophyllins (E 140(ii)) as food additives EFSA Journal Chlorophyllins chlorophyllin a chlorophyllin b chlorin e6 rhodin g7 E 140(ii) |
| title | Scientific Opinion on re‐evaluation of chlorophyllins (E 140(ii)) as food additives |
| title_full | Scientific Opinion on re‐evaluation of chlorophyllins (E 140(ii)) as food additives |
| title_fullStr | Scientific Opinion on re‐evaluation of chlorophyllins (E 140(ii)) as food additives |
| title_full_unstemmed | Scientific Opinion on re‐evaluation of chlorophyllins (E 140(ii)) as food additives |
| title_short | Scientific Opinion on re‐evaluation of chlorophyllins (E 140(ii)) as food additives |
| title_sort | scientific opinion on re evaluation of chlorophyllins e 140 ii as food additives |
| topic | Chlorophyllins chlorophyllin a chlorophyllin b chlorin e6 rhodin g7 E 140(ii) |
| url | https://doi.org/10.2903/j.efsa.2015.4085 |
| work_keys_str_mv | AT efsapanelonfoodadditivesandnutrientsourcesaddedtofoodans scientificopiniononreevaluationofchlorophyllinse140iiasfoodadditives |