Chemotherapy of metastatic colon cancer

Colorectal cancer is one of the leading causes of cancer incidence and mortality. In 2008 inRussian Federation55 719 new cases of colorectal cancer were diagnosed and 37 911 patients died of this disease. A significant progress was achieved in metastatic colorectal cancer treatment during the last d...

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Main Authors: M. Yu. Fedyanin, A. А. Tryakin, S. A. Tjulandin
Format: Article
Language:Russian
Published: “ABV-press” Publishing house”, LLC 2015-02-01
Series:Тазовая хирургия и онкология
Subjects:
Online Access:https://ok.abvpress.ru/jour/article/view/17
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author M. Yu. Fedyanin
A. А. Tryakin
S. A. Tjulandin
author_facet M. Yu. Fedyanin
A. А. Tryakin
S. A. Tjulandin
author_sort M. Yu. Fedyanin
collection DOAJ
description Colorectal cancer is one of the leading causes of cancer incidence and mortality. In 2008 inRussian Federation55 719 new cases of colorectal cancer were diagnosed and 37 911 patients died of this disease. A significant progress was achieved in metastatic colorectal cancer treatment during the last decades. A lot of treatment options became available: from 5-fluoruracil monotherapy to combined treatment treatment schemes including surgery. A group of patients with isolated liver metastases was distinguished, who can achieve 5-year survival rate of 40 % after systemic treatment and surgery. Today, based on clinical data and molecular analysis, we come close to individualized treatment of this patient group. In this literature review results of metastatic colorectal cancer chemotherapy are being analyzed and rational treatment tactic is proposed based on therapy goals.
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spelling doaj.art-0f16f31c05d84874aa3b7bf691f92fd82023-09-03T06:24:43Zrus“ABV-press” Publishing house”, LLCТазовая хирургия и онкология2686-95942015-02-0102263410.17650/2220-3478-2012-0-2-26-3411Chemotherapy of metastatic colon cancerM. Yu. Fedyanin0A. А. Tryakin1S. A. Tjulandin2N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, MoscowN.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, MoscowN.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, MoscowColorectal cancer is one of the leading causes of cancer incidence and mortality. In 2008 inRussian Federation55 719 new cases of colorectal cancer were diagnosed and 37 911 patients died of this disease. A significant progress was achieved in metastatic colorectal cancer treatment during the last decades. A lot of treatment options became available: from 5-fluoruracil monotherapy to combined treatment treatment schemes including surgery. A group of patients with isolated liver metastases was distinguished, who can achieve 5-year survival rate of 40 % after systemic treatment and surgery. Today, based on clinical data and molecular analysis, we come close to individualized treatment of this patient group. In this literature review results of metastatic colorectal cancer chemotherapy are being analyzed and rational treatment tactic is proposed based on therapy goals.https://ok.abvpress.ru/jour/article/view/17metastatic colon cancerchemotherapytreatment tactics
spellingShingle M. Yu. Fedyanin
A. А. Tryakin
S. A. Tjulandin
Chemotherapy of metastatic colon cancer
Тазовая хирургия и онкология
metastatic colon cancer
chemotherapy
treatment tactics
title Chemotherapy of metastatic colon cancer
title_full Chemotherapy of metastatic colon cancer
title_fullStr Chemotherapy of metastatic colon cancer
title_full_unstemmed Chemotherapy of metastatic colon cancer
title_short Chemotherapy of metastatic colon cancer
title_sort chemotherapy of metastatic colon cancer
topic metastatic colon cancer
chemotherapy
treatment tactics
url https://ok.abvpress.ru/jour/article/view/17
work_keys_str_mv AT myufedyanin chemotherapyofmetastaticcoloncancer
AT aatryakin chemotherapyofmetastaticcoloncancer
AT satjulandin chemotherapyofmetastaticcoloncancer