Menthol- and thymol-based ciprofloxacin derivatives against Mycobacterium tuberculosis: in vitro activity, lipophilicity, and computational studies

Menthol- and thymol-based ciprofloxacin derivatives against Mycobacterium tuberculosis: in vitro activity, lipophilicity, and computational studies

Abstract In this work, we investigated the antitubercular properties of Ciprofloxacin derivatives conjugated with menthol and thymol moieties. For the sixteen derivatives, we established minimal inhibitory concentrations (MIC) using isolates of Mycobacterium tuberculosis that were resistant or susce...

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מידע ביבליוגרפי
Main Authors: Daniel Szulczyk, Mateusz Woziński, Michał Koliński, Sebastian Kmiecik, Agnieszka Głogowska, Ewa Augustynowicz-Kopeć, Michał A. Dobrowolski, Piotr Roszkowski, Marta Struga, Krzesimir Ciura
פורמט: Article
שפה:English
יצא לאור: Nature Portfolio 2023-09-01
סדרה:Scientific Reports
גישה מקוונת:https://doi.org/10.1038/s41598-023-43708-4

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