Menthol- and thymol-based ciprofloxacin derivatives against Mycobacterium tuberculosis: in vitro activity, lipophilicity, and computational studies

Menthol- and thymol-based ciprofloxacin derivatives against Mycobacterium tuberculosis: in vitro activity, lipophilicity, and computational studies

Abstract In this work, we investigated the antitubercular properties of Ciprofloxacin derivatives conjugated with menthol and thymol moieties. For the sixteen derivatives, we established minimal inhibitory concentrations (MIC) using isolates of Mycobacterium tuberculosis that were resistant or susce...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид:	Daniel Szulczyk, Mateusz Woziński, Michał Koliński, Sebastian Kmiecik, Agnieszka Głogowska, Ewa Augustynowicz-Kopeć, Michał A. Dobrowolski, Piotr Roszkowski, Marta Struga, Krzesimir Ciura
Формат:	Өгүүллэг
Хэл сонгох:	English
Хэвлэсэн:	Nature Portfolio 2023-09-01
Цуврал:	Scientific Reports
Онлайн хандалт:	https://doi.org/10.1038/s41598-023-43708-4

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