Menthol- and thymol-based ciprofloxacin derivatives against Mycobacterium tuberculosis: in vitro activity, lipophilicity, and computational studies
Abstract In this work, we investigated the antitubercular properties of Ciprofloxacin derivatives conjugated with menthol and thymol moieties. For the sixteen derivatives, we established minimal inhibitory concentrations (MIC) using isolates of Mycobacterium tuberculosis that were resistant or susce...
主要な著者: | , , , , , , , , , |
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フォーマット: | 論文 |
言語: | English |
出版事項: |
Nature Portfolio
2023-09-01
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シリーズ: | Scientific Reports |
オンライン・アクセス: | https://doi.org/10.1038/s41598-023-43708-4 |