Menthol- and thymol-based ciprofloxacin derivatives against Mycobacterium tuberculosis: in vitro activity, lipophilicity, and computational studies

Abstract In this work, we investigated the antitubercular properties of Ciprofloxacin derivatives conjugated with menthol and thymol moieties. For the sixteen derivatives, we established minimal inhibitory concentrations (MIC) using isolates of Mycobacterium tuberculosis that were resistant or susce...

詳細記述

書誌詳細
主要な著者: Daniel Szulczyk, Mateusz Woziński, Michał Koliński, Sebastian Kmiecik, Agnieszka Głogowska, Ewa Augustynowicz-Kopeć, Michał A. Dobrowolski, Piotr Roszkowski, Marta Struga, Krzesimir Ciura
フォーマット: 論文
言語:English
出版事項: Nature Portfolio 2023-09-01
シリーズ:Scientific Reports
オンライン・アクセス:https://doi.org/10.1038/s41598-023-43708-4