A case of recurrent pleural effusion: Can we think beyond tuberculosis and malignancy?

Pleural effusion can occur due to a variety of causes such as infectious, neoplastic, inflammatory, autoimmune, traumatic, etc. Recurrent pleural effusions have always been a diagnostic challenge. Here, we present a case of recurrent exudative pleural effusion in a male patient, which was the first...

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Main Author: Bhumika Vaishnav
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2014-01-01
Series:Medical Journal of Dr. D.Y. Patil University
Subjects:
Online Access:http://www.mjdrdypu.org/article.asp?issn=0975-2870;year=2014;volume=7;issue=2;spage=215;epage=217;aulast=Vaishnav
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author Bhumika Vaishnav
author_facet Bhumika Vaishnav
author_sort Bhumika Vaishnav
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description Pleural effusion can occur due to a variety of causes such as infectious, neoplastic, inflammatory, autoimmune, traumatic, etc. Recurrent pleural effusions have always been a diagnostic challenge. Here, we present a case of recurrent exudative pleural effusion in a male patient, which was the first clinical manifestation of rheumatoid arthritis. Of note was the absence of articular involvement at the onset of the disease. The low glucose concentration, low pH and low C4 level in the pleural fluid were the most valuable findings to distinguish it from tuberculous and malignant pleural effusions. Pleural biopsy also helped in making such a distinction. Thus, in a patient with recurrent pleural effusion, rheumatoid etiology should also be kept in mind as a differential diagnosis.
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spelling doaj.art-0f1a874827504e949c75e606342b52d52022-12-22T03:42:23ZengWolters Kluwer Medknow PublicationsMedical Journal of Dr. D.Y. Patil University0975-28702014-01-017221521710.4103/0975-2870.126351A case of recurrent pleural effusion: Can we think beyond tuberculosis and malignancy?Bhumika VaishnavPleural effusion can occur due to a variety of causes such as infectious, neoplastic, inflammatory, autoimmune, traumatic, etc. Recurrent pleural effusions have always been a diagnostic challenge. Here, we present a case of recurrent exudative pleural effusion in a male patient, which was the first clinical manifestation of rheumatoid arthritis. Of note was the absence of articular involvement at the onset of the disease. The low glucose concentration, low pH and low C4 level in the pleural fluid were the most valuable findings to distinguish it from tuberculous and malignant pleural effusions. Pleural biopsy also helped in making such a distinction. Thus, in a patient with recurrent pleural effusion, rheumatoid etiology should also be kept in mind as a differential diagnosis.http://www.mjdrdypu.org/article.asp?issn=0975-2870;year=2014;volume=7;issue=2;spage=215;epage=217;aulast=VaishnavAnticyclic citrullinated polypeptide antibodyextraarticular diseasepleural effusionrheumatoid arthritis
spellingShingle Bhumika Vaishnav
A case of recurrent pleural effusion: Can we think beyond tuberculosis and malignancy?
Medical Journal of Dr. D.Y. Patil University
Anticyclic citrullinated polypeptide antibody
extraarticular disease
pleural effusion
rheumatoid arthritis
title A case of recurrent pleural effusion: Can we think beyond tuberculosis and malignancy?
title_full A case of recurrent pleural effusion: Can we think beyond tuberculosis and malignancy?
title_fullStr A case of recurrent pleural effusion: Can we think beyond tuberculosis and malignancy?
title_full_unstemmed A case of recurrent pleural effusion: Can we think beyond tuberculosis and malignancy?
title_short A case of recurrent pleural effusion: Can we think beyond tuberculosis and malignancy?
title_sort case of recurrent pleural effusion can we think beyond tuberculosis and malignancy
topic Anticyclic citrullinated polypeptide antibody
extraarticular disease
pleural effusion
rheumatoid arthritis
url http://www.mjdrdypu.org/article.asp?issn=0975-2870;year=2014;volume=7;issue=2;spage=215;epage=217;aulast=Vaishnav
work_keys_str_mv AT bhumikavaishnav acaseofrecurrentpleuraleffusioncanwethinkbeyondtuberculosisandmalignancy
AT bhumikavaishnav caseofrecurrentpleuraleffusioncanwethinkbeyondtuberculosisandmalignancy