Sodium Ferulate Prevents Daunorubicin - Induced Apoptosis in H9c2 Cells via Inhibition of the ERKs Pathway

Sodium Ferulate Prevents Daunorubicin - Induced Apoptosis in H9c2 Cells via Inhibition of the ERKs Pathway

Background: Daunorubicin (DNR)-induced cardiotoxicity, which is closely associated with cardiomyocyte apoptosis, limits the drug's clinical application. The activation of the extracellular regulated protein kinases (ERKs) pathway is responsible for the pro-apoptosis effect of DNR Sodium ferulat...

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Bibliographic Details
Main Authors: Zhi-Juan Wu, Jing Yu, Qiu-Juan Fang, Rui-Xing Wang, Jia-Bian Lian, Rui-Lan He, Hai-Xia Jiao, Mo-Jun Lin
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2015-07-01
Series:Cellular Physiology and Biochemistry
Subjects:
ERKs
Sodium Ferulate
Daunorubicin
Cardio-protection
Apoptosis
H9c2 cell
Online Access:http://www.karger.com/Article/FullText/430179

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