Sex‐specific effects of leptin administration to pregnant mice on the placentae and the metabolic phenotypes of offspring

Sex‐specific effects of leptin administration to pregnant mice on the placentae and the metabolic phenotypes of offspring

Obesity during pregnancy has been shown to increase the risk of metabolic diseases in the offspring. However, the factors within the maternal milieu which affect offspring phenotypes and the underlying mechanisms remain unknown. The adipocyte hormone leptin plays a key role in regulating energy home...

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Bibliographic Details
Main Authors: Elena I. Denisova, Valeria V. Kozhevnikova, Nadezhda M. Bazhan, Elena N. Makarova
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:FEBS Open Bio
Subjects:
developmental programming
leptin
mice
placenta
pregnancy
Online Access:https://doi.org/10.1002/2211-5463.12757

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