Mitochondrial DNA in Visceral Adipose Tissue in Severe Obesity: From Copy Number to D-Loop Methylation

Mitochondrial DNA in Visceral Adipose Tissue in Severe Obesity: From Copy Number to D-Loop Methylation

Background: Peripheral alterations of mitochondrial DNA copy number (mtDNAcn) in obesity and associated co-morbidities have been previously shown. Furthermore, the possibility that methylation could occur in the mtDNA (in particular in the displacement loop, D-Loop) and regulate its functions has be...

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Bibliographic Details
Main Authors: Laura Bordoni, Jessica Perugini, Irene Petracci, Eleonora Di Mercurio, Giovanni Lezoche, Mario Guerrieri, Antonio Giordano, Rosita Gabbianelli
Format: Article
Language:English
Published: IMR Press 2022-05-01
Series:Frontiers in Bioscience-Landmark
Subjects:
tfam
dna methylation
epigenetics
metabolic syndrome
diabetes
nutrigenomics
Online Access:https://www.imrpress.com/journal/FBL/27/6/10.31083/j.fbl2706172

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