Inhibition of Spinal TRPV1 Reduces NMDA Receptor 2B Phosphorylation and Produces Anti-Nociceptive Effects in Mice with Inflammatory Pain

Inhibition of Spinal TRPV1 Reduces NMDA Receptor 2B Phosphorylation and Produces Anti-Nociceptive Effects in Mice with Inflammatory Pain

Transient receptor potential vanilloid 1 (TRPV1) has been implicated in peripheral inflammation and is a mediator of the inflammatory response to various noxious stimuli. However, the interaction between TRPV1 and <i>N</i>-methyl-D-aspartate (NMDA) receptors in the regulation of inflamma...

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Bibliographic Details
Main Authors: Suk-Yun Kang, Su Yeon Seo, Se Kyun Bang, Seong Jin Cho, Kwang-Ho Choi, Yeonhee Ryu
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:International Journal of Molecular Sciences
Subjects:
transient receptor potential vanilloid 1 (TRPV1)
<i>N</i>-methyl-D-aspartate (NMDA)
glutamate
capsazepine
inflammatory pain
Online Access:https://www.mdpi.com/1422-0067/22/20/11177

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