Bosutinib induced pleural effusions: Case report and review of tyrosine kinase inhibitors induced pulmonary toxicity
Tyrosine kinase inhibitors are known to cause pulmonary complications. We report a case of bosutinib related bilateral pleural effusions in a patient with chronic myeloid leukemia. Characteristics of the pleural fluid are presented. We also discuss other tyrosine kinase inhibitors induced pulmonary...
Main Authors: | , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2017-01-01
|
Series: | Respiratory Medicine Case Reports |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2213007117300552 |
_version_ | 1818986115141468160 |
---|---|
author | Natalia I. Moguillansky, MD Hafiz Abdul Moiz Fakih, MD John R. Wingard, MD |
author_facet | Natalia I. Moguillansky, MD Hafiz Abdul Moiz Fakih, MD John R. Wingard, MD |
author_sort | Natalia I. Moguillansky, MD |
collection | DOAJ |
description | Tyrosine kinase inhibitors are known to cause pulmonary complications. We report a case of bosutinib related bilateral pleural effusions in a patient with chronic myeloid leukemia. Characteristics of the pleural fluid are presented. We also discuss other tyrosine kinase inhibitors induced pulmonary toxicities, including pulmonary hypertension and interstitial lung disease. |
first_indexed | 2024-12-20T18:45:39Z |
format | Article |
id | doaj.art-0f20e877fe8c4be8bd61549a4168cd1e |
institution | Directory Open Access Journal |
issn | 2213-0071 |
language | English |
last_indexed | 2024-12-20T18:45:39Z |
publishDate | 2017-01-01 |
publisher | Elsevier |
record_format | Article |
series | Respiratory Medicine Case Reports |
spelling | doaj.art-0f20e877fe8c4be8bd61549a4168cd1e2022-12-21T19:29:42ZengElsevierRespiratory Medicine Case Reports2213-00712017-01-0121C15415710.1016/j.rmcr.2017.05.003Bosutinib induced pleural effusions: Case report and review of tyrosine kinase inhibitors induced pulmonary toxicityNatalia I. Moguillansky, MD0Hafiz Abdul Moiz Fakih, MD1John R. Wingard, MD2University of Florida, Pulmonary, Critical Care and Sleep Medicine, P.O. Box 100225 JHMHC, Gainesville, FL 32610-0225, USAUniversity of Florida, Pulmonary, Critical Care and Sleep Medicine, P.O. Box 100225 JHMHC, Gainesville, FL 32610-0225, USAUniversity of Florida, UF Health Bone Marrow Transplant – Shands Hospital, 1515 SW Archer Rd, Suite #100, Gainesville, FL 32608, USATyrosine kinase inhibitors are known to cause pulmonary complications. We report a case of bosutinib related bilateral pleural effusions in a patient with chronic myeloid leukemia. Characteristics of the pleural fluid are presented. We also discuss other tyrosine kinase inhibitors induced pulmonary toxicities, including pulmonary hypertension and interstitial lung disease.http://www.sciencedirect.com/science/article/pii/S2213007117300552BosutinibTyrosine kinase inhibitorsPleural effusionsPulmonary arterial hypertensionInterstitial lung disease |
spellingShingle | Natalia I. Moguillansky, MD Hafiz Abdul Moiz Fakih, MD John R. Wingard, MD Bosutinib induced pleural effusions: Case report and review of tyrosine kinase inhibitors induced pulmonary toxicity Respiratory Medicine Case Reports Bosutinib Tyrosine kinase inhibitors Pleural effusions Pulmonary arterial hypertension Interstitial lung disease |
title | Bosutinib induced pleural effusions: Case report and review of tyrosine kinase inhibitors induced pulmonary toxicity |
title_full | Bosutinib induced pleural effusions: Case report and review of tyrosine kinase inhibitors induced pulmonary toxicity |
title_fullStr | Bosutinib induced pleural effusions: Case report and review of tyrosine kinase inhibitors induced pulmonary toxicity |
title_full_unstemmed | Bosutinib induced pleural effusions: Case report and review of tyrosine kinase inhibitors induced pulmonary toxicity |
title_short | Bosutinib induced pleural effusions: Case report and review of tyrosine kinase inhibitors induced pulmonary toxicity |
title_sort | bosutinib induced pleural effusions case report and review of tyrosine kinase inhibitors induced pulmonary toxicity |
topic | Bosutinib Tyrosine kinase inhibitors Pleural effusions Pulmonary arterial hypertension Interstitial lung disease |
url | http://www.sciencedirect.com/science/article/pii/S2213007117300552 |
work_keys_str_mv | AT nataliaimoguillanskymd bosutinibinducedpleuraleffusionscasereportandreviewoftyrosinekinaseinhibitorsinducedpulmonarytoxicity AT hafizabdulmoizfakihmd bosutinibinducedpleuraleffusionscasereportandreviewoftyrosinekinaseinhibitorsinducedpulmonarytoxicity AT johnrwingardmd bosutinibinducedpleuraleffusionscasereportandreviewoftyrosinekinaseinhibitorsinducedpulmonarytoxicity |