Genetic variation in angiotensin II type 2 receptor gene influences extent of left ventricular hypertrophy in hypertrophic cardiomyopathy independent of blood pressure

Introduction. Hypertrophic cardiomyopathy (HCM), an inherited primary cardiac disorder mostly caused by defective sarcomeric proteins, serves as a model to investigate left ventricular hypertrophy (LVH). HCM manifests extreme variability in the degree and distribution of LVH, even in patients with t...

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Bibliographic Details
Main Authors: Nadia Carstens, Lize van der Merwe, Miriam Revera, Marshall Heradien, Althea Goosen, Paul A Brink, Johanna C Moolman-Smook
Format: Article
Language:English
Published: SAGE Publications 2011-09-01
Series:Journal of the Renin-Angiotensin-Aldosterone System
Online Access:https://doi.org/10.1177/1470320310390725

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