Genetic variation in angiotensin II type 2 receptor gene influences extent of left ventricular hypertrophy in hypertrophic cardiomyopathy independent of blood pressure
Introduction. Hypertrophic cardiomyopathy (HCM), an inherited primary cardiac disorder mostly caused by defective sarcomeric proteins, serves as a model to investigate left ventricular hypertrophy (LVH). HCM manifests extreme variability in the degree and distribution of LVH, even in patients with t...
Main Authors: | Nadia Carstens, Lize van der Merwe, Miriam Revera, Marshall Heradien, Althea Goosen, Paul A Brink, Johanna C Moolman-Smook |
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Format: | Article |
Language: | English |
Published: |
SAGE Publications
2011-09-01
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Series: | Journal of the Renin-Angiotensin-Aldosterone System |
Online Access: | https://doi.org/10.1177/1470320310390725 |
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