Biological and Pharmacological Characterization of Benzothiazole-Based CK-1δ Inhibitors in Models of Parkinson’s Disease

Biological and Pharmacological Characterization of Benzothiazole-Based CK-1δ Inhibitors in Models of Parkinson’s Disease

Bibliographic Details
Main Authors:	José A. Morales-Garcia, Irene G. Salado, Marina Sanz-San Cristobal, Carmen Gil, Ana Pérez-Castillo, Ana Martínez, Daniel I. Pérez
Format:	Article
Language:	English
Published:	American Chemical Society 2017-08-01
Series:	ACS Omega
Online Access:	http://dx.doi.org/10.1021/acsomega.7b00869

Similar Items

CK1δ in lymphoma: gene expression and mutation analyses and validation of CK1δ kinase activity for therapeutic application
by: Brigitte Sophia Winkler, et al.
Published: (2015-02-01)

CK1δ-Derived Peptides as Novel Tools Inhibiting the Interactions between CK1δ and APP695 to Modulate the Pathogenic Metabolism of APP
by: Aileen Roth, et al.
Published: (2021-06-01)

The Development of CK2 Inhibitors: From Traditional Pharmacology to in Silico Rational Drug Design
by: Giorgio Cozza
Published: (2017-02-01)

A Computational Workflow for the Identification of Novel Fragments Acting as Inhibitors of the Activity of Protein Kinase CK1δ
by: Giovanni Bolcato, et al.
Published: (2021-09-01)

Neurite outgrowth of mature retinal ganglion cells and PC12 cells requires activity of CK1δ and CK1ε.
by: Joachim Bischof, et al.
Published: (2011-01-01)

Comprehensive Characterization of CK1δ-Mediated Tau Phosphorylation in Alzheimer’s Disease
by: Aileen Roth, et al.
Published: (2022-06-01)

CK1δ kinase activity is modulated by Chk1-mediated phosphorylation.
by: Joachim Bischof, et al.
Published: (2013-01-01)

C/EBPβ Regulates TFAM Expression, Mitochondrial Function and Autophagy in Cellular Models of Parkinson’s Disease
by: Ana Sierra-Magro, et al.
Published: (2023-01-01)

CK1δ/ε inhibition induces ULK1-mediated autophagy in tumorigenesis
by: Vivian Weiwen Xue, et al.
Published: (2024-02-01)

Neuroprotective and Anti-Inflammatory Effects of Linoleic Acid in Models of Parkinson’s Disease: The Implication of Lipid Droplets and Lipophagy
by: Jesus Alarcon-Gil, et al.
Published: (2022-07-01)

QSAR Modelling to Identify LRRK2 Inhibitors for Parkinson’s Disease
by: Sebastián-Pérez Víctor, et al.
Published: (2019-02-01)

Rethinking to riluzole mechanism of action: the molecular link among protein kinase CK1δ activity, TDP-43 phosphorylation, and amyotrophic lateral sclerosis pharmacological treatment
by: Maicol Bissaro, et al.
Published: (2019-01-01)

Discovery of novel 2-(4-(benzyloxy)-5-(hydroxyl) phenyl) benzothiazole derivatives as multifunctional MAO-B inhibitors for the treatment of Parkinson’s disease
by: Zhongcheng Cao, et al.
Published: (2023-12-01)

Phosphodiesterase 7 inhibition preserves dopaminergic neurons in cellular and rodent models of Parkinson disease.
by: Jose A Morales-Garcia, et al.
Published: (2011-01-01)

Benzothiazole and Chromone Derivatives as Potential ATR Kinase Inhibitors and Anticancer Agents
by: Mykhaylo Frasinyuk, et al.
Published: (2022-07-01)

Benzothiazole Amides as TRPC3/6 Inhibitors for Gastric Cancer Treatment
by: Yingjie Wei, et al.
Published: (2021-03-01)

Dual Anta-Inhibitors Targeting Protein Kinase CK1δ and A<sub>2A</sub> Adenosine Receptor Useful in Neurodegenerative Disorders
by: Beatrice Francucci, et al.
Published: (2023-06-01)

Casein Kinase 1 Family Member CK1δ/Hrr25 Is Required for Autophagosome Completion
by: Yuting Li, et al.
Published: (2020-07-01)

Zebrafish as model system for the biological characterization of CK1 inhibitors
by: Laura Meier, et al.
Published: (2023-09-01)

Synthesis and biological evaluation of anthracene-9,10 dione derivatives as CK2 inhibitors
by: Priscila López-Rojas, et al.
Published: (2023-12-01)

Design, molecular modelling and synthesis of novel benzothiazole derivatives as BCL-2 inhibitors
by: Hoda S. Ismail, et al.
Published: (2023-09-01)

Structural Basis for the Inhibition of Coronaviral Main Proteases by a Benzothiazole-Based Inhibitor
by: Xiaohui Hu, et al.
Published: (2022-09-01)

Design and Synthesis of New Benzothiazole Compounds as Selective hMAO-B Inhibitors
by: Sinem Ilgın, et al.
Published: (2017-12-01)

Evaluating the pharmacological response in fluorescence microscopy images: The Δm algorithm.
by: Ana I Gómez, et al.
Published: (2019-01-01)

CK1δ stimulates ubiquitination‐dependent proteasomal degradation of ATF4 to promote chemoresistance in gastric Cancer
by: Lifeng Feng, et al.
Published: (2021-10-01)

Synthesis of 2-aryl-benzothiazoles via Ni-catalyzed coupling of benzothiazoles and aryl sulfamates
by: Yu Xiaofeng, et al.
Published: (2020-02-01)

Multitarget Anticancer Agents Based on Histone Deacetylase and Protein Kinase CK2 inhibitors
by: Regina Martínez, et al.
Published: (2020-03-01)

Utility of CK8, CK10, CK13, and CK17 in Differential Diagnostics of Benign Lesions, Laryngeal Dysplasia, and Laryngeal Squamous Cell Carcinoma
by: Novica Boricic, et al.
Published: (2022-12-01)

2-(4-Pentyloxyphenyl)benzothiazole
by: Yasodha Sivasothy, et al.
Published: (2009-08-01)

2-(4-Heptyloxyphenyl)benzothiazole
by: Teck-Leong Lee, et al.
Published: (2009-07-01)

Determination of benzothiazole in grapes and wines
by: S. Karagiannis, et al.
Published: (2000-06-01)

Asemptomatik kreatin kinaz (CK) yüksekliği: Hiper-CK-emi
by: Oğuz Abdullah Uyaroğlu
Published: (2020-06-01)

Structure-Activity Relationships of Benzothiazole-Based Hsp90 C-Terminal-Domain Inhibitors
by: Jaka Dernovšek, et al.
Published: (2021-08-01)

Phosphoproteomic Landscape of AML Cells Treated with the ATP-Competitive CK2 Inhibitor CX-4945
by: Mauro Rosales, et al.
Published: (2021-02-01)

TTBK1 and CK1 inhibitors restore TDP-43 pathology and avoid disease propagation in lymphoblast from Alzheimer’s disease patients
by: Loreto Martinez-Gonzalez, et al.
Published: (2023-08-01)

Diacritic Binding of an Indenoindole Inhibitor by CK2α Paralogs Explored by a Reliable Path to Atomic Resolution CK2α′ Structures
by: Dirk Lindenblatt, et al.
Published: (2019-03-01)

Invasive Lobular Carcinomas Do Not Express Basal Cytokeratin Markers CK5/6, CK14 and CK17
by: Natalya Khilko, et al.
Published: (2010-10-01)

Effect of 6-Benzoyl-benzothiazol-2-one scaffold on the pharmacological profile of α-alkoxyphenylpropionic acid derived PPAR agonists
by: Aurélie Hurtevent, et al.
Published: (2020-01-01)

Formulation and Investigation of CK2 Inhibitor-Loaded Alginate Microbeads with Different Excipients
by: Boglárka Papp, et al.
Published: (2023-11-01)

Repositioning of Etravirine as a Potential CK1ε Inhibitor by Virtual Screening
by: Luis Córdova-Bahena, et al.
Published: (2021-12-01)