ALG3 Promotes Peritoneal Metastasis of Ovarian Cancer through Increasing Interaction of α1,3-mannosylated uPAR and ADAM8

ALG3 Promotes Peritoneal Metastasis of Ovarian Cancer through Increasing Interaction of α1,3-mannosylated uPAR and ADAM8

Peritoneal metastasis is the main cause of poor prognoses and high mortality in ovarian cancer patients. Abnormal protein glycosylation modification is associated with cancer malignancy. Elevated α1,3-mannosyltransferase 3 (ALG3), which catalyzes the α1,3-mannosylation of glycoproteins, has been fou...

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Bibliographic Details
Main Authors: Xinyuan Cui, Xiaosong Pei, Hao Wang, Ping Feng, Huamin Qin, Shuai Liu, Qiu Yan, Jiwei Liu
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Cells
Subjects:
ALG3
α1,3-mannosylation
uPAR
ADAM8
peritoneal metastasis
ovarian cancer
Online Access:https://www.mdpi.com/2073-4409/11/19/3141

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