α-Solanine Inhibits Invasion of Human Prostate Cancer Cell by Suppressing Epithelial-Mesenchymal Transition and MMPs Expression

α-Solanine Inhibits Invasion of Human Prostate Cancer Cell by Suppressing Epithelial-Mesenchymal Transition and MMPs Expression

α-Solanine, a naturally occurring steroidal glycoalkaloid found in nightshade (Solanum nigrum Linn.), was found to inhibit proliferation and induce apoptosis of tumor cells. However, the mechanism involved in suppression of cancer cell metastasis by α-solanine remains unclear. This study investigate...

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Bibliographic Details
Main Authors: Kun-Hung Shen, Alex Chien-Hwa Liao, Jui-Hsiang Hung, Wei-Jiunn Lee, Kai-Chieh Hu, Pin-Tsen Lin, Ruei-Fang Liao, Pin-Shern Chen
Format: Article
Language:English
Published: MDPI AG 2014-08-01
Series:Molecules
Subjects:
α-solanine
invasion
EMT
matrix metalloproteinase
microRNA
Online Access:http://www.mdpi.com/1420-3049/19/8/11896

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