Variables Associated with Short-Term Weight Loss in a Cohort of Patients with Morbid Obesity According to Age and Three Types of Bariatric Surgery
<b>Background</b> The percentage of excess weight lost (%EWL) after bariatric surgery (BS) shows great discrepancies from one individual to another. <b>Objective</b> To evaluate the %EWL one year after BS and to determine the existence of baseline biomarkers associated with w...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-11-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/9/11/3537 |
| _version_ | 1797549008352182272 |
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| author | Maria D. Alvarez-Bermudez Flores Martin-Reyes Luis Ocaña-Wilhelmi Francisco J. Moreno-Ruiz Juan Alcaide Torres Diego Fernandez-Garcia Sergio Valdes Noelia Moreno-Morales Eduardo Garcia-Fuentes Francisco J. Tinahones Lourdes Garrido-Sanchez |
| author_facet | Maria D. Alvarez-Bermudez Flores Martin-Reyes Luis Ocaña-Wilhelmi Francisco J. Moreno-Ruiz Juan Alcaide Torres Diego Fernandez-Garcia Sergio Valdes Noelia Moreno-Morales Eduardo Garcia-Fuentes Francisco J. Tinahones Lourdes Garrido-Sanchez |
| author_sort | Maria D. Alvarez-Bermudez |
| collection | DOAJ |
| description | <b>Background</b> The percentage of excess weight lost (%EWL) after bariatric surgery (BS) shows great discrepancies from one individual to another. <b>Objective</b> To evaluate the %EWL one year after BS and to determine the existence of baseline biomarkers associated with weight loss. <b>Methods</b> We studied 329 patients with morbid obesity undergoing three types of BS (biliopancreatic diversion (BPD), Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (SG)), depending on the %EWL one year after surgery: good responders (GR) (%EWL ≥ 50%) and non-responders (NR) (%EWL < 50%). <b>Results</b> The GR presented a higher percentage of change in anthropometric and biochemical variables compared to the NR group, even within each type of BS. There was a greater percentage of GR among those who underwent RYGB. The patients who underwent SG showed the lowest decrease in biochemical variables, both in GR and NR. Within the GR group, those with a lower age showed greater improvement compared to the other age groups. A %EWL ≥50% was negatively associated with the age and atherogenic index of plasma (AIP), and positively with the type of BS (RYGB). <b>Conclusions</b> The GR group was associated with lower age and AIP and undergoing RYGB. Additionally, those patients who underwent SG showed a lower metabolic improvement. |
| first_indexed | 2024-03-10T15:08:40Z |
| format | Article |
| id | doaj.art-0f2bbcd35e7444c8b99fdd0fae063a61 |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-10T15:08:40Z |
| publishDate | 2020-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-0f2bbcd35e7444c8b99fdd0fae063a612023-11-20T19:31:33ZengMDPI AGJournal of Clinical Medicine2077-03832020-11-01911353710.3390/jcm9113537Variables Associated with Short-Term Weight Loss in a Cohort of Patients with Morbid Obesity According to Age and Three Types of Bariatric SurgeryMaria D. Alvarez-Bermudez0Flores Martin-Reyes1Luis Ocaña-Wilhelmi2Francisco J. Moreno-Ruiz3Juan Alcaide Torres4Diego Fernandez-Garcia5Sergio Valdes6Noelia Moreno-Morales7Eduardo Garcia-Fuentes8Francisco J. Tinahones9Lourdes Garrido-Sanchez10CIBER Fisiopatología Obesidad y Nutrición (CIBERObn), Instituto Salud Carlos III, Km., 228220 Madrid, SpainInstituto de Investigación Biomédica de Málaga-IBIMA, 29010 Málaga, SpainDepartamento de Especialidades Quirúrgicas, Bioquímica e Inmunología, Universidad de Málaga, 29010 Málaga, SpainDepartamento de Especialidades Quirúrgicas, Bioquímica e Inmunología, Universidad de Málaga, 29010 Málaga, SpainUnidad de Gestión Clínica de Endocrinología y Nutrición, Hospital Universitario Virgen de la Victoria, 29010 Málaga, SpainCIBER Fisiopatología Obesidad y Nutrición (CIBERObn), Instituto Salud Carlos III, Km., 228220 Madrid, SpainInstituto de Investigación Biomédica de Málaga-IBIMA, 29010 Málaga, SpainDepartamento Fisioterapia. Facultad Ciencias de la Salud, Universidad de Malaga, 29010 Malaga, SpainInstituto de Investigación Biomédica de Málaga-IBIMA, 29010 Málaga, SpainCIBER Fisiopatología Obesidad y Nutrición (CIBERObn), Instituto Salud Carlos III, Km., 228220 Madrid, SpainCIBER Fisiopatología Obesidad y Nutrición (CIBERObn), Instituto Salud Carlos III, Km., 228220 Madrid, Spain<b>Background</b> The percentage of excess weight lost (%EWL) after bariatric surgery (BS) shows great discrepancies from one individual to another. <b>Objective</b> To evaluate the %EWL one year after BS and to determine the existence of baseline biomarkers associated with weight loss. <b>Methods</b> We studied 329 patients with morbid obesity undergoing three types of BS (biliopancreatic diversion (BPD), Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (SG)), depending on the %EWL one year after surgery: good responders (GR) (%EWL ≥ 50%) and non-responders (NR) (%EWL < 50%). <b>Results</b> The GR presented a higher percentage of change in anthropometric and biochemical variables compared to the NR group, even within each type of BS. There was a greater percentage of GR among those who underwent RYGB. The patients who underwent SG showed the lowest decrease in biochemical variables, both in GR and NR. Within the GR group, those with a lower age showed greater improvement compared to the other age groups. A %EWL ≥50% was negatively associated with the age and atherogenic index of plasma (AIP), and positively with the type of BS (RYGB). <b>Conclusions</b> The GR group was associated with lower age and AIP and undergoing RYGB. Additionally, those patients who underwent SG showed a lower metabolic improvement.https://www.mdpi.com/2077-0383/9/11/3537morbid obesitybariatric surgeryexcess weight loss |
| spellingShingle | Maria D. Alvarez-Bermudez Flores Martin-Reyes Luis Ocaña-Wilhelmi Francisco J. Moreno-Ruiz Juan Alcaide Torres Diego Fernandez-Garcia Sergio Valdes Noelia Moreno-Morales Eduardo Garcia-Fuentes Francisco J. Tinahones Lourdes Garrido-Sanchez Variables Associated with Short-Term Weight Loss in a Cohort of Patients with Morbid Obesity According to Age and Three Types of Bariatric Surgery Journal of Clinical Medicine morbid obesity bariatric surgery excess weight loss |
| title | Variables Associated with Short-Term Weight Loss in a Cohort of Patients with Morbid Obesity According to Age and Three Types of Bariatric Surgery |
| title_full | Variables Associated with Short-Term Weight Loss in a Cohort of Patients with Morbid Obesity According to Age and Three Types of Bariatric Surgery |
| title_fullStr | Variables Associated with Short-Term Weight Loss in a Cohort of Patients with Morbid Obesity According to Age and Three Types of Bariatric Surgery |
| title_full_unstemmed | Variables Associated with Short-Term Weight Loss in a Cohort of Patients with Morbid Obesity According to Age and Three Types of Bariatric Surgery |
| title_short | Variables Associated with Short-Term Weight Loss in a Cohort of Patients with Morbid Obesity According to Age and Three Types of Bariatric Surgery |
| title_sort | variables associated with short term weight loss in a cohort of patients with morbid obesity according to age and three types of bariatric surgery |
| topic | morbid obesity bariatric surgery excess weight loss |
| url | https://www.mdpi.com/2077-0383/9/11/3537 |
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