Characterization of Stress Granule Protein Turnover in Neuronal Progenitor Cells Using Correlative STED and NanoSIMS Imaging

Characterization of Stress Granule Protein Turnover in Neuronal Progenitor Cells Using Correlative STED and NanoSIMS Imaging

Stress granules (SGs) are stress-induced biomolecular condensates which originate primarily from inactivated RNA translation machinery and translation initiation factors. SG formation is an important defensive mechanism for cell survival, while its dysfunction has been linked to neurodegenerative di...

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Bibliographic Details
Main Authors: Stefania Rabasco, Alicia A. Lork, Emmanuel Berlin, Tho D. K. Nguyen, Carl Ernst, Nicolas Locker, Andrew G. Ewing, Nhu T. N. Phan
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:International Journal of Molecular Sciences
Subjects:
stress granules
NanoSIMS
protein turnover
neuronal progenitor cells
mass spectrometry imaging
Online Access:https://www.mdpi.com/1422-0067/24/3/2546

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