Tiltable objective microscope visualizes selectivity for head motion direction and dynamics in zebrafish vestibular system
Signals about head orientation and movement in the vestibular periphery are fundamental to the sense of balance and motion, but difficult to measure systematically during head motion. Here, the authors build a microscope that visualizes neural activity in hair cells and vestibular ganglion cells dur...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2022-12-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-022-35190-9 |
| _version_ | 1797977317164711936 |
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| author | Masashi Tanimoto Ikuko Watakabe Shin-ichi Higashijima |
| author_facet | Masashi Tanimoto Ikuko Watakabe Shin-ichi Higashijima |
| author_sort | Masashi Tanimoto |
| collection | DOAJ |
| description | Signals about head orientation and movement in the vestibular periphery are fundamental to the sense of balance and motion, but difficult to measure systematically during head motion. Here, the authors build a microscope that visualizes neural activity in hair cells and vestibular ganglion cells during 360° head tilt and vibration in zebrafish larvae, and reveal a topographic organization of direction- and static/dynamic stimulus-selective responses. |
| first_indexed | 2024-04-11T05:06:00Z |
| format | Article |
| id | doaj.art-0f2d84eef3e54f998a2cd88c9182dd19 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-04-11T05:06:00Z |
| publishDate | 2022-12-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-0f2d84eef3e54f998a2cd88c9182dd192022-12-25T12:21:17ZengNature PortfolioNature Communications2041-17232022-12-0113111610.1038/s41467-022-35190-9Tiltable objective microscope visualizes selectivity for head motion direction and dynamics in zebrafish vestibular systemMasashi Tanimoto0Ikuko Watakabe1Shin-ichi Higashijima2Division of Behavioral Neurobiology, National Institute for Basic BiologyDivision of Behavioral Neurobiology, National Institute for Basic BiologyDivision of Behavioral Neurobiology, National Institute for Basic BiologySignals about head orientation and movement in the vestibular periphery are fundamental to the sense of balance and motion, but difficult to measure systematically during head motion. Here, the authors build a microscope that visualizes neural activity in hair cells and vestibular ganglion cells during 360° head tilt and vibration in zebrafish larvae, and reveal a topographic organization of direction- and static/dynamic stimulus-selective responses.https://doi.org/10.1038/s41467-022-35190-9 |
| spellingShingle | Masashi Tanimoto Ikuko Watakabe Shin-ichi Higashijima Tiltable objective microscope visualizes selectivity for head motion direction and dynamics in zebrafish vestibular system Nature Communications |
| title | Tiltable objective microscope visualizes selectivity for head motion direction and dynamics in zebrafish vestibular system |
| title_full | Tiltable objective microscope visualizes selectivity for head motion direction and dynamics in zebrafish vestibular system |
| title_fullStr | Tiltable objective microscope visualizes selectivity for head motion direction and dynamics in zebrafish vestibular system |
| title_full_unstemmed | Tiltable objective microscope visualizes selectivity for head motion direction and dynamics in zebrafish vestibular system |
| title_short | Tiltable objective microscope visualizes selectivity for head motion direction and dynamics in zebrafish vestibular system |
| title_sort | tiltable objective microscope visualizes selectivity for head motion direction and dynamics in zebrafish vestibular system |
| url | https://doi.org/10.1038/s41467-022-35190-9 |
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