Scanning a DNA molecule for bound proteins using hybrid magnetic and optical tweezers.

Scanning a DNA molecule for bound proteins using hybrid magnetic and optical tweezers.

The functional state of the genome is determined by its interactions with proteins that bind, modify, and move along the DNA. To determine the positions and binding strength of proteins localized on DNA we have developed a combined magnetic and optical tweezers apparatus that allows for both sensiti...

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Bibliographic Details
Main Authors: Marijn T J van Loenhout, Iwijn De Vlaminck, Benedetta Flebus, Johan F den Blanken, Ludovit P Zweifel, Koen M Hooning, Jacob W J Kerssemakers, Cees Dekker
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3670887?pdf=render

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