Nepheliosyne B, a New Polyacetylenic Acid from the New Caledonian Marine Sponge Niphates sp.

A new C47 polyoxygenated acetylenic acid, nepheliosyne B (2), along with the previously described nepheliosyne A (1), have been isolated from the New Caledonian marine sponge Niphates sp. Their structures have been elucidated on the basis of extensive spectroscopic analyses. These metabolites exhibi...

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Main Authors: Patrick Auberger, Philippe Amade, Mohamed Mehiri, Jean Vacelet, Vincent Guérineau, Maeva Dufies, Nathalie Legrave, Souhir Hamrouni-Buonomo
Format: Article
Language:English
Published: MDPI AG 2013-06-01
Series:Marine Drugs
Subjects:
Online Access:http://www.mdpi.com/1660-3397/11/7/2282
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author Patrick Auberger
Philippe Amade
Mohamed Mehiri
Jean Vacelet
Vincent Guérineau
Maeva Dufies
Nathalie Legrave
Souhir Hamrouni-Buonomo
author_facet Patrick Auberger
Philippe Amade
Mohamed Mehiri
Jean Vacelet
Vincent Guérineau
Maeva Dufies
Nathalie Legrave
Souhir Hamrouni-Buonomo
author_sort Patrick Auberger
collection DOAJ
description A new C47 polyoxygenated acetylenic acid, nepheliosyne B (2), along with the previously described nepheliosyne A (1), have been isolated from the New Caledonian marine sponge Niphates sp. Their structures have been elucidated on the basis of extensive spectroscopic analyses. These metabolites exhibited a moderate cytotoxicity against K562, U266, SKM1, and Kasumi cancer cell lines.
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spelling doaj.art-0f37ead6ef9742358f1171529986444d2022-12-22T04:23:37ZengMDPI AGMarine Drugs1660-33972013-06-011172282229210.3390/md11072282Nepheliosyne B, a New Polyacetylenic Acid from the New Caledonian Marine Sponge Niphates sp.Patrick AubergerPhilippe AmadeMohamed MehiriJean VaceletVincent GuérineauMaeva DufiesNathalie LegraveSouhir Hamrouni-BuonomoA new C47 polyoxygenated acetylenic acid, nepheliosyne B (2), along with the previously described nepheliosyne A (1), have been isolated from the New Caledonian marine sponge Niphates sp. Their structures have been elucidated on the basis of extensive spectroscopic analyses. These metabolites exhibited a moderate cytotoxicity against K562, U266, SKM1, and Kasumi cancer cell lines.http://www.mdpi.com/1660-3397/11/7/2282marine natural productshighly oxygenated polyacetylenesmarine spongesPoriferaHaplosclerida
spellingShingle Patrick Auberger
Philippe Amade
Mohamed Mehiri
Jean Vacelet
Vincent Guérineau
Maeva Dufies
Nathalie Legrave
Souhir Hamrouni-Buonomo
Nepheliosyne B, a New Polyacetylenic Acid from the New Caledonian Marine Sponge Niphates sp.
Marine Drugs
marine natural products
highly oxygenated polyacetylenes
marine sponges
Porifera
Haplosclerida
title Nepheliosyne B, a New Polyacetylenic Acid from the New Caledonian Marine Sponge Niphates sp.
title_full Nepheliosyne B, a New Polyacetylenic Acid from the New Caledonian Marine Sponge Niphates sp.
title_fullStr Nepheliosyne B, a New Polyacetylenic Acid from the New Caledonian Marine Sponge Niphates sp.
title_full_unstemmed Nepheliosyne B, a New Polyacetylenic Acid from the New Caledonian Marine Sponge Niphates sp.
title_short Nepheliosyne B, a New Polyacetylenic Acid from the New Caledonian Marine Sponge Niphates sp.
title_sort nepheliosyne b a new polyacetylenic acid from the new caledonian marine sponge niphates sp
topic marine natural products
highly oxygenated polyacetylenes
marine sponges
Porifera
Haplosclerida
url http://www.mdpi.com/1660-3397/11/7/2282
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