Interferon alpha inducible protein 6 is a negative regulator of innate immune responses by modulating RIG-I activation

Interferon alpha inducible protein 6 is a negative regulator of innate immune responses by modulating RIG-I activation

Interferons (IFNs), IFN-stimulated genes (ISGs), and inflammatory cytokines mediate innate immune responses, and are essential to establish an antiviral response. Within the innate immune responses, retinoic acid-inducible gene I (RIG-I) is a key sensor of virus infections, mediating the transcripti...

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Bibliographic Details
Main Authors: Laura Villamayor, Vanessa Rivero, Darío López-García, David J. Topham, Luis Martínez-Sobrido, Aitor Nogales, Marta L. DeDiego
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Immunology
Subjects:
IFI6
interferon
innate immunity
RIG-I
RNA binding
inflammation
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1105309/full

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