A systematic review of health disparities research in deep brain stimulation surgery for Parkinson’s disease
BackgroundDeep brain stimulation (DBS) is the primary surgical intervention for Parkinson’s disease (PD) patients with insufficient response to medication, significantly improving motor symptoms and quality of life. Despite FDA approval for over two decades, access to this therapy remains limited. T...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-10-01
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| Series: | Frontiers in Human Neuroscience |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fnhum.2023.1269401/full |
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| author | Adeel A. Memon Kate Gelman Joseph Melott Rebecca Billings Michelle Fullard Corina Catiul Svjetlana Miocinovic Amy W. Amara |
| author_facet | Adeel A. Memon Kate Gelman Joseph Melott Rebecca Billings Michelle Fullard Corina Catiul Svjetlana Miocinovic Amy W. Amara |
| author_sort | Adeel A. Memon |
| collection | DOAJ |
| description | BackgroundDeep brain stimulation (DBS) is the primary surgical intervention for Parkinson’s disease (PD) patients with insufficient response to medication, significantly improving motor symptoms and quality of life. Despite FDA approval for over two decades, access to this therapy remains limited. This systematic review aims to evaluate the influence of gender, race/ethnicity, socioeconomic status, and age on health disparities associated with DBS for PD, providing an overview of current research in this field.MethodsA systematic literature search was conducted in PubMed/MEDLINE, Embase, Web of Science and Cochrane databases from 1960 to September 12th, 2023, following Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines. Studies that examine the disparities in accessing DBS among patients with PD were included, comparing different demographic factors. Findings were synthesized and presented narratively to identify and understand DBS disparities.ResultsAfter screening for relevance, 25 studies published between 1960 and 2023 were included, with 16 studies meeting full-text review criteria. While reviewing the references of the 16 articles, two additional studies were included, bringing the total number of included studies to 18. Most studies originated from the United States (44%). The identified studies were categorized as identifying disparities, understanding disparities, or reducing disparities. The majority focused on identifying disparities (72%), while fewer studies delved into understanding the underlying factors (28%). No studies evaluated strategies for reducing disparities. The findings indicate that elderly, female, and Black people, as well as those from low socioeconomic backgrounds and developing countries face greater obstacles in accessing DBS for PD.ConclusionThis study highlights factors contributing to disparities in DBS utilization for PD, including race, gender, and socioeconomic status. Public health policymakers, practitioners, and clinicians should recognize these inequalities and work toward reducing disparities, particularly among vulnerable populations. |
| first_indexed | 2024-03-11T15:24:50Z |
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| id | doaj.art-0f3d626d20fd4607aa4a208c74e1e66d |
| institution | Directory Open Access Journal |
| issn | 1662-5161 |
| language | English |
| last_indexed | 2024-03-11T15:24:50Z |
| publishDate | 2023-10-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Human Neuroscience |
| spelling | doaj.art-0f3d626d20fd4607aa4a208c74e1e66d2023-10-27T22:06:07ZengFrontiers Media S.A.Frontiers in Human Neuroscience1662-51612023-10-011710.3389/fnhum.2023.12694011269401A systematic review of health disparities research in deep brain stimulation surgery for Parkinson’s diseaseAdeel A. Memon0Kate Gelman1Joseph Melott2Rebecca Billings3Michelle Fullard4Corina Catiul5Svjetlana Miocinovic6Amy W. Amara7Department of Neurology, Rockefeller Neuroscience Institute, West Virginia University, Morgantown, WV, United StatesSchool of Medicine, West Virginia University, Morgantown, WV, United StatesSchool of Medicine, West Virginia University, Morgantown, WV, United StatesUAB Libraries, University of Alabama at Birmingham, Birmingham, AL, United StatesDepartment of Neurology, University of Colorado, Aurora, CO, United StatesDepartment of Neurology, University of Alabama at Birmingham, Birmingham, AL, United StatesDepartment of Neurology, Emory University, Atlanta, GA, United StatesDepartment of Neurology, University of Colorado, Aurora, CO, United StatesBackgroundDeep brain stimulation (DBS) is the primary surgical intervention for Parkinson’s disease (PD) patients with insufficient response to medication, significantly improving motor symptoms and quality of life. Despite FDA approval for over two decades, access to this therapy remains limited. This systematic review aims to evaluate the influence of gender, race/ethnicity, socioeconomic status, and age on health disparities associated with DBS for PD, providing an overview of current research in this field.MethodsA systematic literature search was conducted in PubMed/MEDLINE, Embase, Web of Science and Cochrane databases from 1960 to September 12th, 2023, following Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines. Studies that examine the disparities in accessing DBS among patients with PD were included, comparing different demographic factors. Findings were synthesized and presented narratively to identify and understand DBS disparities.ResultsAfter screening for relevance, 25 studies published between 1960 and 2023 were included, with 16 studies meeting full-text review criteria. While reviewing the references of the 16 articles, two additional studies were included, bringing the total number of included studies to 18. Most studies originated from the United States (44%). The identified studies were categorized as identifying disparities, understanding disparities, or reducing disparities. The majority focused on identifying disparities (72%), while fewer studies delved into understanding the underlying factors (28%). No studies evaluated strategies for reducing disparities. The findings indicate that elderly, female, and Black people, as well as those from low socioeconomic backgrounds and developing countries face greater obstacles in accessing DBS for PD.ConclusionThis study highlights factors contributing to disparities in DBS utilization for PD, including race, gender, and socioeconomic status. Public health policymakers, practitioners, and clinicians should recognize these inequalities and work toward reducing disparities, particularly among vulnerable populations.https://www.frontiersin.org/articles/10.3389/fnhum.2023.1269401/fulldeep brain stimulationParkinson’s diseasehealth disparitiesracial disparitiesgender disparitiessocioeconomic disparities |
| spellingShingle | Adeel A. Memon Kate Gelman Joseph Melott Rebecca Billings Michelle Fullard Corina Catiul Svjetlana Miocinovic Amy W. Amara A systematic review of health disparities research in deep brain stimulation surgery for Parkinson’s disease Frontiers in Human Neuroscience deep brain stimulation Parkinson’s disease health disparities racial disparities gender disparities socioeconomic disparities |
| title | A systematic review of health disparities research in deep brain stimulation surgery for Parkinson’s disease |
| title_full | A systematic review of health disparities research in deep brain stimulation surgery for Parkinson’s disease |
| title_fullStr | A systematic review of health disparities research in deep brain stimulation surgery for Parkinson’s disease |
| title_full_unstemmed | A systematic review of health disparities research in deep brain stimulation surgery for Parkinson’s disease |
| title_short | A systematic review of health disparities research in deep brain stimulation surgery for Parkinson’s disease |
| title_sort | systematic review of health disparities research in deep brain stimulation surgery for parkinson s disease |
| topic | deep brain stimulation Parkinson’s disease health disparities racial disparities gender disparities socioeconomic disparities |
| url | https://www.frontiersin.org/articles/10.3389/fnhum.2023.1269401/full |
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