Association between Bone Mineral Density and Albuminuria: Cross-Sectional Analysis of Data from the 2011 Korea National Health and Nutrition Examination Survey V-2
BackgroundAlbuminuria is known to be independently associated with progression of renal and cardiovascular disease. However, little is known regarding the exact relationship between albuminuria and bone mineral density (BMD). The aim of this population-based study conducted in Korea was to identify...
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| Format: | Article |
| Language: | English |
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Korean Endocrine Society
2018-05-01
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| Series: | Endocrinology and Metabolism |
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| Online Access: | https://e-enm.org/Synapse/Data/PDFData/2008ENM/enm-33-211.pdf |
| _version_ | 1818749510346604544 |
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| author | Tae Yang Yu Ha-Young Kim Jeong Mi Lee Dae Ho Lee Chung Gu Cho |
| author_facet | Tae Yang Yu Ha-Young Kim Jeong Mi Lee Dae Ho Lee Chung Gu Cho |
| author_sort | Tae Yang Yu |
| collection | DOAJ |
| description | BackgroundAlbuminuria is known to be independently associated with progression of renal and cardiovascular disease. However, little is known regarding the exact relationship between albuminuria and bone mineral density (BMD). The aim of this population-based study conducted in Korea was to identify the association between albuminuria and BMD.MethodsWe performed a cross-sectional analysis of data from the Korea National Health and Nutrition Examination Survey (KNHANES V-2) 2011. BMD was measured for total hip (TH), femur neck (FN), and lumbar spine (LS). Analysis of covariance was used to compare BMD levels between the groups at the TH, FN, and LS sites, after adjusting for age. Separate analyses were performed according to sex; women were divided into two groups according to menopausal status and each group was subdivided into three according to urine albumin-to-creatinine ratio (level 1, <30 mg/g; level 2, 30 to 299 mg/g; level 3, ≥300 mg/g).ResultsData on a total of 1,831 adults (857 men and 974 women) were analyzed. In postmenopausal women, after adjusting for age, BMD of TH tended to decrease as levels of albuminuria increased (0.767±0.117, 0.757±0.129, 0.752±0.118, respectively; P=0.040). However, there was no significant difference in BMD according to albuminuria level in premenopausal women and men.ConclusionLevel of albuminuria was closely related with BMD of TH in postmenopausal women, after adjusting for age, but there was no significant relationship between albuminuria and BMD in premenopausal women and men. |
| first_indexed | 2024-12-18T04:04:55Z |
| format | Article |
| id | doaj.art-0f3dcd2e31c34760bdc494882d2751b6 |
| institution | Directory Open Access Journal |
| issn | 2093-596X 2093-5978 |
| language | English |
| last_indexed | 2024-12-18T04:04:55Z |
| publishDate | 2018-05-01 |
| publisher | Korean Endocrine Society |
| record_format | Article |
| series | Endocrinology and Metabolism |
| spelling | doaj.art-0f3dcd2e31c34760bdc494882d2751b62022-12-21T21:21:36ZengKorean Endocrine SocietyEndocrinology and Metabolism2093-596X2093-59782018-05-0133221121810.3803/EnM.2018.33.2.211Association between Bone Mineral Density and Albuminuria: Cross-Sectional Analysis of Data from the 2011 Korea National Health and Nutrition Examination Survey V-2Tae Yang Yu0Ha-Young Kim1Jeong Mi Lee2Dae Ho Lee3Chung Gu Cho4Division of Endocrinology and Metabolism, Department of Internal Medicine, Wonkwang University School of Medicine, Iksan, .KoreaDivision of Endocrinology and Metabolism, Department of Internal Medicine, Wonkwang University Sanbon Hospital, Wonkwang University School of Medicine, Gunpo, .KoreaDepartment of Public Health, Wonkwang University School of Medicine, Iksan, .KoreaDivision of Endocrinology and Metabolism, Department of Internal Medicine, Gachon University Gil Medical Center, Gachon University College of Medicine, Incheon, .KoreaDivision of Endocrinology and Metabolism, Department of Internal Medicine, Wonkwang University School of Medicine, Iksan, .KoreaBackgroundAlbuminuria is known to be independently associated with progression of renal and cardiovascular disease. However, little is known regarding the exact relationship between albuminuria and bone mineral density (BMD). The aim of this population-based study conducted in Korea was to identify the association between albuminuria and BMD.MethodsWe performed a cross-sectional analysis of data from the Korea National Health and Nutrition Examination Survey (KNHANES V-2) 2011. BMD was measured for total hip (TH), femur neck (FN), and lumbar spine (LS). Analysis of covariance was used to compare BMD levels between the groups at the TH, FN, and LS sites, after adjusting for age. Separate analyses were performed according to sex; women were divided into two groups according to menopausal status and each group was subdivided into three according to urine albumin-to-creatinine ratio (level 1, <30 mg/g; level 2, 30 to 299 mg/g; level 3, ≥300 mg/g).ResultsData on a total of 1,831 adults (857 men and 974 women) were analyzed. In postmenopausal women, after adjusting for age, BMD of TH tended to decrease as levels of albuminuria increased (0.767±0.117, 0.757±0.129, 0.752±0.118, respectively; P=0.040). However, there was no significant difference in BMD according to albuminuria level in premenopausal women and men.ConclusionLevel of albuminuria was closely related with BMD of TH in postmenopausal women, after adjusting for age, but there was no significant relationship between albuminuria and BMD in premenopausal women and men.https://e-enm.org/Synapse/Data/PDFData/2008ENM/enm-33-211.pdfAlbuminuriaBone densityMetabolic syndromeOsteoporosis, postmenopausal |
| spellingShingle | Tae Yang Yu Ha-Young Kim Jeong Mi Lee Dae Ho Lee Chung Gu Cho Association between Bone Mineral Density and Albuminuria: Cross-Sectional Analysis of Data from the 2011 Korea National Health and Nutrition Examination Survey V-2 Endocrinology and Metabolism Albuminuria Bone density Metabolic syndrome Osteoporosis, postmenopausal |
| title | Association between Bone Mineral Density and Albuminuria: Cross-Sectional Analysis of Data from the 2011 Korea National Health and Nutrition Examination Survey V-2 |
| title_full | Association between Bone Mineral Density and Albuminuria: Cross-Sectional Analysis of Data from the 2011 Korea National Health and Nutrition Examination Survey V-2 |
| title_fullStr | Association between Bone Mineral Density and Albuminuria: Cross-Sectional Analysis of Data from the 2011 Korea National Health and Nutrition Examination Survey V-2 |
| title_full_unstemmed | Association between Bone Mineral Density and Albuminuria: Cross-Sectional Analysis of Data from the 2011 Korea National Health and Nutrition Examination Survey V-2 |
| title_short | Association between Bone Mineral Density and Albuminuria: Cross-Sectional Analysis of Data from the 2011 Korea National Health and Nutrition Examination Survey V-2 |
| title_sort | association between bone mineral density and albuminuria cross sectional analysis of data from the 2011 korea national health and nutrition examination survey v 2 |
| topic | Albuminuria Bone density Metabolic syndrome Osteoporosis, postmenopausal |
| url | https://e-enm.org/Synapse/Data/PDFData/2008ENM/enm-33-211.pdf |
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