The Exocrine Pancreas in Cystic Fibrosis in the Era of CFTR Modulation: A Mini Review
Cystic fibrosis (CF) is a common disorder of autosomal recessive inheritance, that once conferred a life expectancy of only a few months. Over recent years, significant advances have been made to CF therapeutic approaches, changing the face of the disease, and facilitating the partial restoration of...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-06-01
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| Series: | Frontiers in Pediatrics |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fped.2022.914790/full |
| _version_ | 1828315515641135104 |
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| author | Isabelle R. McKay Chee Y. Ooi Chee Y. Ooi |
| author_facet | Isabelle R. McKay Chee Y. Ooi Chee Y. Ooi |
| author_sort | Isabelle R. McKay |
| collection | DOAJ |
| description | Cystic fibrosis (CF) is a common disorder of autosomal recessive inheritance, that once conferred a life expectancy of only a few months. Over recent years, significant advances have been made to CF therapeutic approaches, changing the face of the disease, and facilitating the partial restoration of pancreatic function. This mini review summarizes the current landscape of exocrine pancreatic management in CF and explores areas for future direction and development. |
| first_indexed | 2024-04-13T17:01:04Z |
| format | Article |
| id | doaj.art-0f405b1c68784a92a5bf1b2fac0e676a |
| institution | Directory Open Access Journal |
| issn | 2296-2360 |
| language | English |
| last_indexed | 2024-04-13T17:01:04Z |
| publishDate | 2022-06-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Pediatrics |
| spelling | doaj.art-0f405b1c68784a92a5bf1b2fac0e676a2022-12-22T02:38:38ZengFrontiers Media S.A.Frontiers in Pediatrics2296-23602022-06-011010.3389/fped.2022.914790914790The Exocrine Pancreas in Cystic Fibrosis in the Era of CFTR Modulation: A Mini ReviewIsabelle R. McKay0Chee Y. Ooi1Chee Y. Ooi2Wagga Wagga Base Hospital, Wagga Wagga, NSW, AustraliaSchool of Clinical Medicine, Discipline of Paediatrics and Child Health, Randwick Clinical Campus, University of New South Wales (UNSW) Medicine and Health, University of New South Wales, Sydney, NSW, AustraliaDepartment of Gastroenterology, Sydney Children's Hospital Randwick, Randwick, NSW, AustraliaCystic fibrosis (CF) is a common disorder of autosomal recessive inheritance, that once conferred a life expectancy of only a few months. Over recent years, significant advances have been made to CF therapeutic approaches, changing the face of the disease, and facilitating the partial restoration of pancreatic function. This mini review summarizes the current landscape of exocrine pancreatic management in CF and explores areas for future direction and development.https://www.frontiersin.org/articles/10.3389/fped.2022.914790/fullcystic fibrosisexocrine pancreasCFTR modulatorspancreatitisprecision medicine |
| spellingShingle | Isabelle R. McKay Chee Y. Ooi Chee Y. Ooi The Exocrine Pancreas in Cystic Fibrosis in the Era of CFTR Modulation: A Mini Review Frontiers in Pediatrics cystic fibrosis exocrine pancreas CFTR modulators pancreatitis precision medicine |
| title | The Exocrine Pancreas in Cystic Fibrosis in the Era of CFTR Modulation: A Mini Review |
| title_full | The Exocrine Pancreas in Cystic Fibrosis in the Era of CFTR Modulation: A Mini Review |
| title_fullStr | The Exocrine Pancreas in Cystic Fibrosis in the Era of CFTR Modulation: A Mini Review |
| title_full_unstemmed | The Exocrine Pancreas in Cystic Fibrosis in the Era of CFTR Modulation: A Mini Review |
| title_short | The Exocrine Pancreas in Cystic Fibrosis in the Era of CFTR Modulation: A Mini Review |
| title_sort | exocrine pancreas in cystic fibrosis in the era of cftr modulation a mini review |
| topic | cystic fibrosis exocrine pancreas CFTR modulators pancreatitis precision medicine |
| url | https://www.frontiersin.org/articles/10.3389/fped.2022.914790/full |
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