Inhibition of projections from the basolateral amygdala to the entorhinal cortex disrupts the acquisition of contextual fear

Inhibition of projections from the basolateral amygdala to the entorhinal cortex disrupts the acquisition of contextual fear

The development of excessive fear and/or stress responses to environmental cues such as contexts associated with a traumatic event is a hallmark of post-traumatic stress disorder (PTSD). The basolateral amygdala (BLA) has been implicated as a key structure mediating contextual fear conditioning. I...

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Bibliographic Details
Main Authors: Dennis R. Sparta, Jim eSmithuis, Alice eStamatakis, Josh eJennings, Pranish eKantak, Randall eUng, Garret eStuber
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-05-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
Amygdala
Hippocampus
Fear conditioning
Glutamate
optogenetics
halorhodopsin
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnbeh.2014.00129/full

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