The vascular wall in postmenopausal women with hypothyroidism and hypertension

AIM: To study a relationship between thyroid function and the stiffness of great arteries in postmenopausal women with arterial hypertension (AH)/MATERIAL AND METHODS: The trial enrolled 76 postmenopausal patients with clinical hypothyroidism (CHT) (n=24) or subclinical hypothyroidism (SCHT) (n=52)...

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Main Authors: O Iu Riabtseva, Ia A Orlova, Z N Blankova, T E Chazova, F T Ageev
Format: Article
Language:Russian
Published: "Consilium Medicum" Publishing house 2013-10-01
Series:Терапевтический архив
Subjects:
Online Access:https://ter-arkhiv.ru/0040-3660/article/view/31351
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author O Iu Riabtseva
Ia A Orlova
Z N Blankova
T E Chazova
F T Ageev
author_facet O Iu Riabtseva
Ia A Orlova
Z N Blankova
T E Chazova
F T Ageev
author_sort O Iu Riabtseva
collection DOAJ
description AIM: To study a relationship between thyroid function and the stiffness of great arteries in postmenopausal women with arterial hypertension (AH)/MATERIAL AND METHODS: The trial enrolled 76 postmenopausal patients with clinical hypothyroidism (CHT) (n=24) or subclinical hypothyroidism (SCHT) (n=52) and AH; a control group consisted of 40 postmenopausal women with euthyroidism. Body mass index (BMI), waist and hip circumferences, blood pressure (BP), thyroid-stimulating hormone (TSH), free thyroxine, free triiodothyronine, total cholesterol, triglycerides were determines; volumetric sphygmography was performed. Brachial-ankle pulse wave velocity (baPWV) was measured; cardio-ankle vascular index (CAVI) and ankle-brachial index (ABI) were determined/RESULTS: The patients with CHT or SCHT and the controls were matched for age, BMI, BP, and heart rate. TSH levels in patients with SCHT (6.23 (5.27; 8.22) µU/ml) and in those with CHT (11.8 (9.09; 22.7) µU/ml) were statistically significantly higher than in the control group (2.25 (1.5; 2.72) µU/ml) (p
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spelling doaj.art-0f43d29b0c784aeba56c26e7f5658ef82022-12-22T01:18:40Zrus"Consilium Medicum" Publishing houseТерапевтический архив0040-36602309-53422013-10-018510646928367The vascular wall in postmenopausal women with hypothyroidism and hypertensionO Iu RiabtsevaIa A OrlovaZ N BlankovaT E ChazovaF T AgeevAIM: To study a relationship between thyroid function and the stiffness of great arteries in postmenopausal women with arterial hypertension (AH)/MATERIAL AND METHODS: The trial enrolled 76 postmenopausal patients with clinical hypothyroidism (CHT) (n=24) or subclinical hypothyroidism (SCHT) (n=52) and AH; a control group consisted of 40 postmenopausal women with euthyroidism. Body mass index (BMI), waist and hip circumferences, blood pressure (BP), thyroid-stimulating hormone (TSH), free thyroxine, free triiodothyronine, total cholesterol, triglycerides were determines; volumetric sphygmography was performed. Brachial-ankle pulse wave velocity (baPWV) was measured; cardio-ankle vascular index (CAVI) and ankle-brachial index (ABI) were determined/RESULTS: The patients with CHT or SCHT and the controls were matched for age, BMI, BP, and heart rate. TSH levels in patients with SCHT (6.23 (5.27; 8.22) µU/ml) and in those with CHT (11.8 (9.09; 22.7) µU/ml) were statistically significantly higher than in the control group (2.25 (1.5; 2.72) µU/ml) (phttps://ter-arkhiv.ru/0040-3660/article/view/31351hypothyroidismarterial stiffnessarterial hypertension
spellingShingle O Iu Riabtseva
Ia A Orlova
Z N Blankova
T E Chazova
F T Ageev
The vascular wall in postmenopausal women with hypothyroidism and hypertension
Терапевтический архив
hypothyroidism
arterial stiffness
arterial hypertension
title The vascular wall in postmenopausal women with hypothyroidism and hypertension
title_full The vascular wall in postmenopausal women with hypothyroidism and hypertension
title_fullStr The vascular wall in postmenopausal women with hypothyroidism and hypertension
title_full_unstemmed The vascular wall in postmenopausal women with hypothyroidism and hypertension
title_short The vascular wall in postmenopausal women with hypothyroidism and hypertension
title_sort vascular wall in postmenopausal women with hypothyroidism and hypertension
topic hypothyroidism
arterial stiffness
arterial hypertension
url https://ter-arkhiv.ru/0040-3660/article/view/31351
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