EXPRESSION MICRORNA IN LARYNX CANCER
MicroRNA are nonprotein-coding small ribonucleic acids controlling gene expression at post-transcriptional level. MicroRNA technically could controll 2/3 of human genome. At the present study abnormal expression of microRNA-18а, -21, -155, -200а, -200с, -205, -221, -494 in malignant tissue of squamo...
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| Format: | Article |
| Language: | Russian |
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Russian Academy of Sciences, Tomsk National Research Medical Center
2016-02-01
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| Series: | Сибирский онкологический журнал |
| Subjects: | |
| Online Access: | https://www.siboncoj.ru/jour/article/view/140 |
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| author | E. G. Nikitina O. V. Cheremisina V. A. Bychkov D. E. Kulbakin E. L. Choinzonov V. N. Stegniy N. V. Litviakov |
| author_facet | E. G. Nikitina O. V. Cheremisina V. A. Bychkov D. E. Kulbakin E. L. Choinzonov V. N. Stegniy N. V. Litviakov |
| author_sort | E. G. Nikitina |
| collection | DOAJ |
| description | MicroRNA are nonprotein-coding small ribonucleic acids controlling gene expression at post-transcriptional level. MicroRNA technically could controll 2/3 of human genome. At the present study abnormal expression of microRNA-18а, -21, -155, -200а, -200с, -205, -221, -494 in malignant tissue of squamous cell larynx carcinoma of 46 patients were studied. There was no statistically significant correlation between microRNA expression and pathological characteristics. Our data showed that oncogenic microRNA-21, -155, -205 were overexpressed as well as oncosypression microRNA-200a were underexpressed in larynx cancer compared to adjacent normal epithelium. |
| first_indexed | 2024-04-10T01:55:02Z |
| format | Article |
| id | doaj.art-0f44b85652c54195991c4e8e469bf341 |
| institution | Directory Open Access Journal |
| issn | 1814-4861 2312-3168 |
| language | Russian |
| last_indexed | 2025-03-14T10:10:24Z |
| publishDate | 2016-02-01 |
| publisher | Russian Academy of Sciences, Tomsk National Research Medical Center |
| record_format | Article |
| series | Сибирский онкологический журнал |
| spelling | doaj.art-0f44b85652c54195991c4e8e469bf3412025-03-02T11:16:04ZrusRussian Academy of Sciences, Tomsk National Research Medical CenterСибирский онкологический журнал1814-48612312-31682016-02-01124652140EXPRESSION MICRORNA IN LARYNX CANCERE. G. Nikitina0O. V. Cheremisina1V. A. Bychkov2D. E. Kulbakin3E. L. Choinzonov4V. N. Stegniy5N. V. Litviakov6Tomsk Cancer Research Institute, Tomsk; Tomsk State University, TomskTomsk Cancer Research Institute, TomskTomsk Cancer Research Institute, TomskTomsk Cancer Research Institute, TomskTomsk Cancer Research Institute, TomskTomsk State University, TomskTomsk Cancer Research Institute, Tomsk; Tomsk State University, TomskMicroRNA are nonprotein-coding small ribonucleic acids controlling gene expression at post-transcriptional level. MicroRNA technically could controll 2/3 of human genome. At the present study abnormal expression of microRNA-18а, -21, -155, -200а, -200с, -205, -221, -494 in malignant tissue of squamous cell larynx carcinoma of 46 patients were studied. There was no statistically significant correlation between microRNA expression and pathological characteristics. Our data showed that oncogenic microRNA-21, -155, -205 were overexpressed as well as oncosypression microRNA-200a were underexpressed in larynx cancer compared to adjacent normal epithelium.https://www.siboncoj.ru/jour/article/view/140larynx cancermicrornaexpression |
| spellingShingle | E. G. Nikitina O. V. Cheremisina V. A. Bychkov D. E. Kulbakin E. L. Choinzonov V. N. Stegniy N. V. Litviakov EXPRESSION MICRORNA IN LARYNX CANCER Сибирский онкологический журнал larynx cancer microrna expression |
| title | EXPRESSION MICRORNA IN LARYNX CANCER |
| title_full | EXPRESSION MICRORNA IN LARYNX CANCER |
| title_fullStr | EXPRESSION MICRORNA IN LARYNX CANCER |
| title_full_unstemmed | EXPRESSION MICRORNA IN LARYNX CANCER |
| title_short | EXPRESSION MICRORNA IN LARYNX CANCER |
| title_sort | expression microrna in larynx cancer |
| topic | larynx cancer microrna expression |
| url | https://www.siboncoj.ru/jour/article/view/140 |
| work_keys_str_mv | AT egnikitina expressionmicrornainlarynxcancer AT ovcheremisina expressionmicrornainlarynxcancer AT vabychkov expressionmicrornainlarynxcancer AT dekulbakin expressionmicrornainlarynxcancer AT elchoinzonov expressionmicrornainlarynxcancer AT vnstegniy expressionmicrornainlarynxcancer AT nvlitviakov expressionmicrornainlarynxcancer |