Complex Interventions Deserve Complex Evaluations: A Transdisciplinary Approach to Evaluation of a Preventive Personalized Medicine Intervention
Non-communicable diseases (NCDs) are the largest cause of disability and death globally. The human and financial costs of NCDs have raised questions of sustainability for many health systems. Personalized, preventive health interventions are an innovative way to address NCDs, but it is difficult to...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-02-01
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| Series: | Frontiers in Public Health |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fpubh.2022.793137/full |
| _version_ | 1798031852386123776 |
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| author | Elise M. Garton Elise M. Garton Serdar Savaş Christopher Pell Elena V. Syurina Karien Stronks Tomris Cesuroglu Tomris Cesuroglu |
| author_facet | Elise M. Garton Elise M. Garton Serdar Savaş Christopher Pell Elena V. Syurina Karien Stronks Tomris Cesuroglu Tomris Cesuroglu |
| author_sort | Elise M. Garton |
| collection | DOAJ |
| description | Non-communicable diseases (NCDs) are the largest cause of disability and death globally. The human and financial costs of NCDs have raised questions of sustainability for many health systems. Personalized, preventive health interventions are an innovative way to address NCDs, but it is difficult to measure their effectiveness using standard evaluation methods. This article describes a novel approach to evaluation by coupling transdisciplinary methods with realist theory to design and pilot a health outcomes evaluation for a personalized medicine approach to NCD prevention in Istanbul, Turkey. Research and practice stakeholders contributed to study design, research questions, validation of results, and recommendations through interactive workshops, consistent dialogue, and reflection. They co-created a customized outcome measurement framework and recommendations that promote sustainability and continuous improvement of future evaluations. The participatory methods helped resolve the dichotomy between patient, practitioner, and researcher focus in the evaluation and improved stakeholders' data literacy. This research contributes to the body of evidence advocating for the use of non-standard methods such as transdisciplinary research to evaluate the effectiveness of complex interventions. The results of the pilot evaluation are also presented as a case study. |
| first_indexed | 2024-04-11T20:03:09Z |
| format | Article |
| id | doaj.art-0f4baca7e60c4a0eb1e4ff88be9325aa |
| institution | Directory Open Access Journal |
| issn | 2296-2565 |
| language | English |
| last_indexed | 2024-04-11T20:03:09Z |
| publishDate | 2022-02-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Public Health |
| spelling | doaj.art-0f4baca7e60c4a0eb1e4ff88be9325aa2022-12-22T04:05:26ZengFrontiers Media S.A.Frontiers in Public Health2296-25652022-02-011010.3389/fpubh.2022.793137793137Complex Interventions Deserve Complex Evaluations: A Transdisciplinary Approach to Evaluation of a Preventive Personalized Medicine InterventionElise M. Garton0Elise M. Garton1Serdar Savaş2Christopher Pell3Elena V. Syurina4Karien Stronks5Tomris Cesuroglu6Tomris Cesuroglu7Athena Institute, Faculty of Science, Vrije Universiteit Amsterdam, Amsterdam, NetherlandsGentest Institute, Istanbul, TurkeyGentest Institute, Istanbul, TurkeyAmsterdam Institute for Global Health and Development, Amsterdam, NetherlandsAthena Institute, Faculty of Science, Vrije Universiteit Amsterdam, Amsterdam, NetherlandsAcademic Medical Centre, University of Amsterdam, Amsterdam, NetherlandsAthena Institute, Faculty of Science, Vrije Universiteit Amsterdam, Amsterdam, NetherlandsGentest Institute, Istanbul, TurkeyNon-communicable diseases (NCDs) are the largest cause of disability and death globally. The human and financial costs of NCDs have raised questions of sustainability for many health systems. Personalized, preventive health interventions are an innovative way to address NCDs, but it is difficult to measure their effectiveness using standard evaluation methods. This article describes a novel approach to evaluation by coupling transdisciplinary methods with realist theory to design and pilot a health outcomes evaluation for a personalized medicine approach to NCD prevention in Istanbul, Turkey. Research and practice stakeholders contributed to study design, research questions, validation of results, and recommendations through interactive workshops, consistent dialogue, and reflection. They co-created a customized outcome measurement framework and recommendations that promote sustainability and continuous improvement of future evaluations. The participatory methods helped resolve the dichotomy between patient, practitioner, and researcher focus in the evaluation and improved stakeholders' data literacy. This research contributes to the body of evidence advocating for the use of non-standard methods such as transdisciplinary research to evaluate the effectiveness of complex interventions. The results of the pilot evaluation are also presented as a case study.https://www.frontiersin.org/articles/10.3389/fpubh.2022.793137/fulltransdisciplinary researchrealist evaluationpersonalized healthcarenon-communicable diseasespreventive healthcareprogram evaluation |
| spellingShingle | Elise M. Garton Elise M. Garton Serdar Savaş Christopher Pell Elena V. Syurina Karien Stronks Tomris Cesuroglu Tomris Cesuroglu Complex Interventions Deserve Complex Evaluations: A Transdisciplinary Approach to Evaluation of a Preventive Personalized Medicine Intervention Frontiers in Public Health transdisciplinary research realist evaluation personalized healthcare non-communicable diseases preventive healthcare program evaluation |
| title | Complex Interventions Deserve Complex Evaluations: A Transdisciplinary Approach to Evaluation of a Preventive Personalized Medicine Intervention |
| title_full | Complex Interventions Deserve Complex Evaluations: A Transdisciplinary Approach to Evaluation of a Preventive Personalized Medicine Intervention |
| title_fullStr | Complex Interventions Deserve Complex Evaluations: A Transdisciplinary Approach to Evaluation of a Preventive Personalized Medicine Intervention |
| title_full_unstemmed | Complex Interventions Deserve Complex Evaluations: A Transdisciplinary Approach to Evaluation of a Preventive Personalized Medicine Intervention |
| title_short | Complex Interventions Deserve Complex Evaluations: A Transdisciplinary Approach to Evaluation of a Preventive Personalized Medicine Intervention |
| title_sort | complex interventions deserve complex evaluations a transdisciplinary approach to evaluation of a preventive personalized medicine intervention |
| topic | transdisciplinary research realist evaluation personalized healthcare non-communicable diseases preventive healthcare program evaluation |
| url | https://www.frontiersin.org/articles/10.3389/fpubh.2022.793137/full |
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