DOT1L Methyltransferase Regulates Calcium Influx in Erythroid Progenitor Cells in Response to Erythropoietin

DOT1L Methyltransferase Regulates Calcium Influx in Erythroid Progenitor Cells in Response to Erythropoietin

Erythropoietin (EPO) signaling plays a vital role in erythropoiesis by regulating proliferation and lineage-specific differentiation of murine hematopoietic progenitor cells (HPCs). An important downstream response of EPO signaling is calcium (Ca<sup>2+</sup>) influx, which is regulated...

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Bibliographic Details
Main Authors: Yi Feng, Shaon Borosha, Anamika Ratri, Eun Bee Lee, Huizhen Wang, Timothy A. Fields, William H. Kinsey, Jay L. Vivian, M. A. Karim Rumi, Patrick E. Fields
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:International Journal of Molecular Sciences
Subjects:
DOT1L
erythroid progenitors
erythropoietin
TRPC6
calcium influx
Online Access:https://www.mdpi.com/1422-0067/23/9/5137

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