Pathophysiological features of chronic cerebrovascular diseases and possibilities of complex neuroprotective therapy

The article discusses the principles of neuroprotective therapy as a pathogenetically justified direction in chronic cerebrovascular diseases (CVD). The results of numerous clinical trials demonstrated efficacy, safety, a wide range of pharmacological effects and good tolerability of the powerful an...

Full description

Bibliographic Details
Main Authors: E. V. Kostenko, L. V. Petrova
Format: Article
Language:Russian
Published: Remedium Group LLC 2019-03-01
Series:Медицинский совет
Subjects:
Online Access:https://www.med-sovet.pro/jour/article/view/2894
_version_ 1797841607648608256
author E. V. Kostenko
L. V. Petrova
author_facet E. V. Kostenko
L. V. Petrova
author_sort E. V. Kostenko
collection DOAJ
description The article discusses the principles of neuroprotective therapy as a pathogenetically justified direction in chronic cerebrovascular diseases (CVD). The results of numerous clinical trials demonstrated efficacy, safety, a wide range of pharmacological effects and good tolerability of the powerful antioxidant Idebenone (Neyromet), as well as domestic cytoprotector, Choline alphosceratus of (Cerepro®), affecting the basic pathophysiological processes of the ischemic cascade at CVD. The role of rational multimodal pharmacotherapy of CVD, which provides the necessary energy for the processes of neuroprotection and neuroplasticity of brain cells, is emphasized.
first_indexed 2024-04-09T16:34:02Z
format Article
id doaj.art-0f4f5a9f307d4eb18fc151e0ba8bd301
institution Directory Open Access Journal
issn 2079-701X
2658-5790
language Russian
last_indexed 2024-04-09T16:34:02Z
publishDate 2019-03-01
publisher Remedium Group LLC
record_format Article
series Медицинский совет
spelling doaj.art-0f4f5a9f307d4eb18fc151e0ba8bd3012023-04-23T06:56:59ZrusRemedium Group LLCМедицинский совет2079-701X2658-57902019-03-0101243010.21518/2079-701X-2019-1-24-302818Pathophysiological features of chronic cerebrovascular diseases and possibilities of complex neuroprotective therapyE. V. Kostenko0L. V. Petrova1Moscow State Autonomous Healthcare Institution «Moscow Scientific and Practical Centre of Medical Rehabilitation, Restorative and Sports Medicine of Moscow Health Care Department»; Federal State Budgetary Educational Institution of Higher Education «Pirogov Russian National Research Medical University» of the Ministry of Health of RussiaMoscow State Autonomous Healthcare Institution «Moscow Scientific and Practical Centre of Medical Rehabilitation, Restorative and Sports Medicine of Moscow Health Care Department»The article discusses the principles of neuroprotective therapy as a pathogenetically justified direction in chronic cerebrovascular diseases (CVD). The results of numerous clinical trials demonstrated efficacy, safety, a wide range of pharmacological effects and good tolerability of the powerful antioxidant Idebenone (Neyromet), as well as domestic cytoprotector, Choline alphosceratus of (Cerepro®), affecting the basic pathophysiological processes of the ischemic cascade at CVD. The role of rational multimodal pharmacotherapy of CVD, which provides the necessary energy for the processes of neuroprotection and neuroplasticity of brain cells, is emphasized.https://www.med-sovet.pro/jour/article/view/2894chronic cerebrovascular diseases (cvd)ischemic cascadeneurocytoprotectionneuroplasticityidebenonecholine alphosceratuscomprehensive rehabilitationmultimodal therapycomplex rehabilitationcognitive function
spellingShingle E. V. Kostenko
L. V. Petrova
Pathophysiological features of chronic cerebrovascular diseases and possibilities of complex neuroprotective therapy
Медицинский совет
chronic cerebrovascular diseases (cvd)
ischemic cascade
neurocytoprotection
neuroplasticity
idebenone
choline alphosceratus
comprehensive rehabilitation
multimodal therapy
complex rehabilitation
cognitive function
title Pathophysiological features of chronic cerebrovascular diseases and possibilities of complex neuroprotective therapy
title_full Pathophysiological features of chronic cerebrovascular diseases and possibilities of complex neuroprotective therapy
title_fullStr Pathophysiological features of chronic cerebrovascular diseases and possibilities of complex neuroprotective therapy
title_full_unstemmed Pathophysiological features of chronic cerebrovascular diseases and possibilities of complex neuroprotective therapy
title_short Pathophysiological features of chronic cerebrovascular diseases and possibilities of complex neuroprotective therapy
title_sort pathophysiological features of chronic cerebrovascular diseases and possibilities of complex neuroprotective therapy
topic chronic cerebrovascular diseases (cvd)
ischemic cascade
neurocytoprotection
neuroplasticity
idebenone
choline alphosceratus
comprehensive rehabilitation
multimodal therapy
complex rehabilitation
cognitive function
url https://www.med-sovet.pro/jour/article/view/2894
work_keys_str_mv AT evkostenko pathophysiologicalfeaturesofchroniccerebrovasculardiseasesandpossibilitiesofcomplexneuroprotectivetherapy
AT lvpetrova pathophysiologicalfeaturesofchroniccerebrovasculardiseasesandpossibilitiesofcomplexneuroprotectivetherapy