Benzopyranones from the Endophytic Fungus Hyalodendriella sp. Ponipodef12 and Their Bioactivities
The endophytic fungus Hyalodendriella sp. Ponipodef12 was isolated from the hybrid ‘Neva’ of Populus deltoides Marsh × P. nigra L. In this study, four benzopyranones were isolated from the ethyl acetate extract of Hyalodendriella sp. Ponipodef12, and identified as palmariol B (1), 4-hydroxymellein (...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2012-09-01
|
| Series: | Molecules |
| Subjects: | |
| Online Access: | http://www.mdpi.com/1420-3049/17/10/11303 |
| _version_ | 1830374218712219648 |
|---|---|
| author | Ligang Zhou Youliang Peng Lingyun Zhong Liang Xu Jingfeng Lou Ziling Mao Xiangjie Meng Mingan Wang |
| author_facet | Ligang Zhou Youliang Peng Lingyun Zhong Liang Xu Jingfeng Lou Ziling Mao Xiangjie Meng Mingan Wang |
| author_sort | Ligang Zhou |
| collection | DOAJ |
| description | The endophytic fungus Hyalodendriella sp. Ponipodef12 was isolated from the hybrid ‘Neva’ of Populus deltoides Marsh × P. nigra L. In this study, four benzopyranones were isolated from the ethyl acetate extract of Hyalodendriella sp. Ponipodef12, and identified as palmariol B (1), 4-hydroxymellein (2), alternariol 9-methyl ether (3), and botrallin (4) by means of physicochemical and spectroscopic analysis. All the compounds were evaluated for their antibacterial, antifungal, antinematodal and acetylcholinesterase inhibitory activities. 4-Hydroxymellein (2) exhibited stronger antibacterial activity than the other compounds. Palmariol B (1) showed stronger antimicrobial, antinematodal and acetylcholinesterase inhibitory activities than alternariol 9-methyl ether (3) which indicated that the chlorine substitution at position 2 may contribute to its bioactivity. The results indicate the potential of this endophytic fungus as a source of bioactive benzopyranones. |
| first_indexed | 2024-12-20T07:32:47Z |
| format | Article |
| id | doaj.art-0f52ea0ff9be408d9f7c1bb9793bd65a |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-12-20T07:32:47Z |
| publishDate | 2012-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-0f52ea0ff9be408d9f7c1bb9793bd65a2022-12-21T19:48:21ZengMDPI AGMolecules1420-30492012-09-011710113031131410.3390/molecules171011303Benzopyranones from the Endophytic Fungus Hyalodendriella sp. Ponipodef12 and Their BioactivitiesLigang ZhouYouliang PengLingyun ZhongLiang XuJingfeng LouZiling MaoXiangjie MengMingan WangThe endophytic fungus Hyalodendriella sp. Ponipodef12 was isolated from the hybrid ‘Neva’ of Populus deltoides Marsh × P. nigra L. In this study, four benzopyranones were isolated from the ethyl acetate extract of Hyalodendriella sp. Ponipodef12, and identified as palmariol B (1), 4-hydroxymellein (2), alternariol 9-methyl ether (3), and botrallin (4) by means of physicochemical and spectroscopic analysis. All the compounds were evaluated for their antibacterial, antifungal, antinematodal and acetylcholinesterase inhibitory activities. 4-Hydroxymellein (2) exhibited stronger antibacterial activity than the other compounds. Palmariol B (1) showed stronger antimicrobial, antinematodal and acetylcholinesterase inhibitory activities than alternariol 9-methyl ether (3) which indicated that the chlorine substitution at position 2 may contribute to its bioactivity. The results indicate the potential of this endophytic fungus as a source of bioactive benzopyranones.http://www.mdpi.com/1420-3049/17/10/11303poplar hybrid ‘Neva’ endophytic fungusHyalodendriella sp. Ponipodef12benzopyranonespalmariol B4-hydroxymelleinalternariol 9-methyl etherbotrallinbioactivities |
| spellingShingle | Ligang Zhou Youliang Peng Lingyun Zhong Liang Xu Jingfeng Lou Ziling Mao Xiangjie Meng Mingan Wang Benzopyranones from the Endophytic Fungus Hyalodendriella sp. Ponipodef12 and Their Bioactivities Molecules poplar hybrid ‘Neva’ endophytic fungus Hyalodendriella sp. Ponipodef12 benzopyranones palmariol B 4-hydroxymellein alternariol 9-methyl ether botrallin bioactivities |
| title | Benzopyranones from the Endophytic Fungus Hyalodendriella sp. Ponipodef12 and Their Bioactivities |
| title_full | Benzopyranones from the Endophytic Fungus Hyalodendriella sp. Ponipodef12 and Their Bioactivities |
| title_fullStr | Benzopyranones from the Endophytic Fungus Hyalodendriella sp. Ponipodef12 and Their Bioactivities |
| title_full_unstemmed | Benzopyranones from the Endophytic Fungus Hyalodendriella sp. Ponipodef12 and Their Bioactivities |
| title_short | Benzopyranones from the Endophytic Fungus Hyalodendriella sp. Ponipodef12 and Their Bioactivities |
| title_sort | benzopyranones from the endophytic fungus hyalodendriella sp ponipodef12 and their bioactivities |
| topic | poplar hybrid ‘Neva’ endophytic fungus Hyalodendriella sp. Ponipodef12 benzopyranones palmariol B 4-hydroxymellein alternariol 9-methyl ether botrallin bioactivities |
| url | http://www.mdpi.com/1420-3049/17/10/11303 |
| work_keys_str_mv | AT ligangzhou benzopyranonesfromtheendophyticfungushyalodendriellaspponipodef12andtheirbioactivities AT youliangpeng benzopyranonesfromtheendophyticfungushyalodendriellaspponipodef12andtheirbioactivities AT lingyunzhong benzopyranonesfromtheendophyticfungushyalodendriellaspponipodef12andtheirbioactivities AT liangxu benzopyranonesfromtheendophyticfungushyalodendriellaspponipodef12andtheirbioactivities AT jingfenglou benzopyranonesfromtheendophyticfungushyalodendriellaspponipodef12andtheirbioactivities AT zilingmao benzopyranonesfromtheendophyticfungushyalodendriellaspponipodef12andtheirbioactivities AT xiangjiemeng benzopyranonesfromtheendophyticfungushyalodendriellaspponipodef12andtheirbioactivities AT minganwang benzopyranonesfromtheendophyticfungushyalodendriellaspponipodef12andtheirbioactivities |