Surface electroencephalographic neurofeedback improves sustained attention in ADHD: a meta-analysis of randomized controlled trials
Abstract Background The efficacy of surface electroencephalographic neurofeedback (EEG-NF) for improving attentional performance assessed by laboratory measures in patients with attention-deficit/hyperactivity disorder (ADHD) remains unclear. Methods Following the PRISMA guidelines, the PubMed, Emba...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2022-12-01
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| Series: | Child and Adolescent Psychiatry and Mental Health |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13034-022-00543-1 |
| _version_ | 1828087236837507072 |
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| author | Hsien‐Jane Chiu Cheuk-Kwan Sun Hsin-Yi Fan Ruu‐Fen Tzang Ming-Yu Wang Ying-Chih Cheng Yu-Shian Cheng Pin-Yang Yeh Weilun Chung |
| author_facet | Hsien‐Jane Chiu Cheuk-Kwan Sun Hsin-Yi Fan Ruu‐Fen Tzang Ming-Yu Wang Ying-Chih Cheng Yu-Shian Cheng Pin-Yang Yeh Weilun Chung |
| author_sort | Hsien‐Jane Chiu |
| collection | DOAJ |
| description | Abstract Background The efficacy of surface electroencephalographic neurofeedback (EEG-NF) for improving attentional performance assessed by laboratory measures in patients with attention-deficit/hyperactivity disorder (ADHD) remains unclear. Methods Following the PRISMA guidelines, the PubMed, Embase, ClinicalKey, Cochrane CENTRAL, ScienceDirect, Web of Science, and ClinicalTrials.gov databases were systematically searched for randomized controlled trials on the efficacy of surface EEG-NF against ADHD focusing on attentional performance evaluated by laboratory measures from inception to January 2022. Results Fourteen eligible studies were analyzed. Of the 718 participants involved, 429 diagnosed with ADHD received EEG-NF treatment. Significant improvement in attentional performance in ADHD subjects receiving EEG-NF was noted compared to their comparators (p < 0.01). Besides, there was a significant EEG-NF-associated beneficial effect on sustained attention (Hedges’ g = 0.32, p < 0.01), whereas the impact on selective attention (p = 0.57) and working memory (p = 0.59) was limited. Moreover, protocol including beta wave enhancement was superior to that only focusing on reducing theta/beta ratio or modulation of slow cortical potential. Subgroup analyses showed that three sessions per week of EEG-NF produced the best effect, while the efficacy of surface EEG-NF was much poorer (Hedges’ g = 0.05) when only studies that blinded their participants from knowledge of treatment allocation were included. No significant difference was noted in the improvement of attentional performance 6–12 months after EEG-NF intervention (n = 3, p = 0.42). Conclusions Our results demonstrated the satisfactory effectiveness of surface EEG-NF for improving sustained attention, especially when beta wave enhancement was included, despite its failure to sustain a long-term effect. Further large-scale trials are warranted to support our findings. |
| first_indexed | 2024-04-11T05:09:18Z |
| format | Article |
| id | doaj.art-0f5b5c4bb1494e45aa6676ecc2eebee0 |
| institution | Directory Open Access Journal |
| issn | 1753-2000 |
| language | English |
| last_indexed | 2024-04-11T05:09:18Z |
| publishDate | 2022-12-01 |
| publisher | BMC |
| record_format | Article |
| series | Child and Adolescent Psychiatry and Mental Health |
| spelling | doaj.art-0f5b5c4bb1494e45aa6676ecc2eebee02022-12-25T12:05:30ZengBMCChild and Adolescent Psychiatry and Mental Health1753-20002022-12-0116111310.1186/s13034-022-00543-1Surface electroencephalographic neurofeedback improves sustained attention in ADHD: a meta-analysis of randomized controlled trialsHsien‐Jane Chiu0Cheuk-Kwan Sun1Hsin-Yi Fan2Ruu‐Fen Tzang3Ming-Yu Wang4Ying-Chih Cheng5Yu-Shian Cheng6Pin-Yang Yeh7Weilun Chung8Taoyuan Psychiatric Center, Ministry of Health and WelfareDepartment of Emergency Medicine, E-Da Hospital, I-Shou UniversityDepartment of Psychiatry, Tsyr-Huey Mental HospitalDepartment of Psychiatry, Mackay Memorial HospitalDepartment of Psychiatry, China Medical University Hsinchu Hospital, China Medical UniversityDepartment of Psychiatry, China Medical University Hsinchu Hospital, China Medical UniversityDepartment of Psychiatry, Tsyr-Huey Mental HospitalDepartment of Psychology, College of Medical and Health Science, Asia UniversityDepartment of Psychiatry, Tsyr-Huey Mental HospitalAbstract Background The efficacy of surface electroencephalographic neurofeedback (EEG-NF) for improving attentional performance assessed by laboratory measures in patients with attention-deficit/hyperactivity disorder (ADHD) remains unclear. Methods Following the PRISMA guidelines, the PubMed, Embase, ClinicalKey, Cochrane CENTRAL, ScienceDirect, Web of Science, and ClinicalTrials.gov databases were systematically searched for randomized controlled trials on the efficacy of surface EEG-NF against ADHD focusing on attentional performance evaluated by laboratory measures from inception to January 2022. Results Fourteen eligible studies were analyzed. Of the 718 participants involved, 429 diagnosed with ADHD received EEG-NF treatment. Significant improvement in attentional performance in ADHD subjects receiving EEG-NF was noted compared to their comparators (p < 0.01). Besides, there was a significant EEG-NF-associated beneficial effect on sustained attention (Hedges’ g = 0.32, p < 0.01), whereas the impact on selective attention (p = 0.57) and working memory (p = 0.59) was limited. Moreover, protocol including beta wave enhancement was superior to that only focusing on reducing theta/beta ratio or modulation of slow cortical potential. Subgroup analyses showed that three sessions per week of EEG-NF produced the best effect, while the efficacy of surface EEG-NF was much poorer (Hedges’ g = 0.05) when only studies that blinded their participants from knowledge of treatment allocation were included. No significant difference was noted in the improvement of attentional performance 6–12 months after EEG-NF intervention (n = 3, p = 0.42). Conclusions Our results demonstrated the satisfactory effectiveness of surface EEG-NF for improving sustained attention, especially when beta wave enhancement was included, despite its failure to sustain a long-term effect. Further large-scale trials are warranted to support our findings.https://doi.org/10.1186/s13034-022-00543-1BiofeedbackNeurocognitive testsAttentional performanceInformant bias |
| spellingShingle | Hsien‐Jane Chiu Cheuk-Kwan Sun Hsin-Yi Fan Ruu‐Fen Tzang Ming-Yu Wang Ying-Chih Cheng Yu-Shian Cheng Pin-Yang Yeh Weilun Chung Surface electroencephalographic neurofeedback improves sustained attention in ADHD: a meta-analysis of randomized controlled trials Child and Adolescent Psychiatry and Mental Health Biofeedback Neurocognitive tests Attentional performance Informant bias |
| title | Surface electroencephalographic neurofeedback improves sustained attention in ADHD: a meta-analysis of randomized controlled trials |
| title_full | Surface electroencephalographic neurofeedback improves sustained attention in ADHD: a meta-analysis of randomized controlled trials |
| title_fullStr | Surface electroencephalographic neurofeedback improves sustained attention in ADHD: a meta-analysis of randomized controlled trials |
| title_full_unstemmed | Surface electroencephalographic neurofeedback improves sustained attention in ADHD: a meta-analysis of randomized controlled trials |
| title_short | Surface electroencephalographic neurofeedback improves sustained attention in ADHD: a meta-analysis of randomized controlled trials |
| title_sort | surface electroencephalographic neurofeedback improves sustained attention in adhd a meta analysis of randomized controlled trials |
| topic | Biofeedback Neurocognitive tests Attentional performance Informant bias |
| url | https://doi.org/10.1186/s13034-022-00543-1 |
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