Lack of Induction of RBD-Specific Neutralizing Antibodies despite Repeated Heterologous SARS-CoV-2 Vaccination Leading to Seroconversion and Establishment of T Cell-Specific Memory in a Patient in Remission of Multiple Myeloma

Lack of Induction of RBD-Specific Neutralizing Antibodies despite Repeated Heterologous SARS-CoV-2 Vaccination Leading to Seroconversion and Establishment of T Cell-Specific Memory in a Patient in Remission of Multiple Myeloma

Background: Prophylactic vaccination against infectious diseases may induce a state of long-term protection in the otherwise healthy host. However, the situation is less predictable in immunocompromised patients and may require adjustment of vaccination schedules and/or basic therapy. Methods: A pat...

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Bibliographic Details
Main Authors: Bernhard Kratzer, Doris Trapin, Pia Gattinger, Teresa Oberhofer, Al Nasar Ahmed Sehgal, Petra Waidhofer-Söllner, Arno Rottal, Ulrike Körmöczi, Katharina Grabmeier-Pfistershammer, Gerhard H. Kopetzky, Franz Tischer, Rudolf Valenta, Winfried F. Pickl
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Vaccines
Subjects:
SARS-CoV-2
prophylactic vaccination
multiple myeloma
pomalidomide
Online Access:https://www.mdpi.com/2076-393X/10/3/374

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