A retrospective study on atrial fibrillation after coronary artery bypass grafting surgery at The National Heart Institute, Kuala Lumpur [version 2; referees: 2 approved]
Background: Atrial fibrillation (AF) is common after cardiac surgery and has been associated with poor outcome and increased resource utilization. The main objective of this study is to determine the incidence of POAF in Malaysia and identify the predictors of developing POAF. The secondary outcome...
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F1000 Research Ltd
2018-08-01
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| Online Access: | https://f1000research.com/articles/7-164/v2 |
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| author | Ahmad Farouk Musa Chou Zhao Quan Low Zheng Xin Trived Soni Jeswant Dillon Yuen Kah Hay Rusli Bin Nordin |
| author_facet | Ahmad Farouk Musa Chou Zhao Quan Low Zheng Xin Trived Soni Jeswant Dillon Yuen Kah Hay Rusli Bin Nordin |
| author_sort | Ahmad Farouk Musa |
| collection | DOAJ |
| description | Background: Atrial fibrillation (AF) is common after cardiac surgery and has been associated with poor outcome and increased resource utilization. The main objective of this study is to determine the incidence of POAF in Malaysia and identify the predictors of developing POAF. The secondary outcome of this study would be to investigate the difference in mortality and morbidity rates and the duration of intensive care unit (ICU), high dependency unit (HDU) and hospital stay between the two. Methods: This is a retrospective single-center, cross sectional study conducted at the National Heart Institute, Malaysia. Medical records of 637 who underwent coronary artery bypass grafting (CABG) surgery in 2015 were accrued. Pre-operative, operative and post-operative information were subsequently collected on a pre-formulated data collection sheet. Data were then analyzed using IBM SPSS v23. Results: The incidence of POAF in our study stands at 28.7% with a mean onset of 45±33 hours post operatively. Variables with independent association with POAF include advancing age, Indian population, history of chronic kidney disease, left ventricular ejection fraction and beta-blocker treatment. The mortality rate is significantly higher statistically (p < 0.05), and similarly the incidence of stroke. The incidence of other post-operative complications was also significantly higher statistically. The duration of ICU, HDU and hospital stays were statistically longer (p < 0.001) with higher rates of ICU readmissions and reintubations seen. Conclusion: We conclude that the incidence of POAF in Malaysia is comparable to the figures in Western countries, making POAF one of the most commonly encountered condition after CABG with similar higher rates of mortality, poor outcomes and longer duration of stay, and therefore increased cost of care. Strategies to reduce the incidence of AF after cardiac surgery should favorably affect surgical outcomes and reduce utilization of resources and thus lower cost of care. |
| first_indexed | 2024-12-20T07:11:01Z |
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| language | English |
| last_indexed | 2024-12-20T07:11:01Z |
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| spelling | doaj.art-0f5db558c271485a800fb0277de74ae42022-12-21T19:48:54ZengF1000 Research LtdF1000Research2046-14022018-08-01710.12688/f1000research.13244.216902A retrospective study on atrial fibrillation after coronary artery bypass grafting surgery at The National Heart Institute, Kuala Lumpur [version 2; referees: 2 approved]Ahmad Farouk Musa0Chou Zhao Quan1Low Zheng Xin2Trived Soni3Jeswant Dillon4Yuen Kah Hay5Rusli Bin Nordin6School of Medicine and Health Sciences, Monash University Malaysia, Subang Jaya, MalaysiaSchool of Medicine and Health Sciences, Monash University Malaysia, Subang Jaya, MalaysiaSchool of Medicine and Health Sciences, Monash University Malaysia, Subang Jaya, MalaysiaSchool of Medicine and Health Sciences, Monash University Malaysia, Subang Jaya, MalaysiaDepartment of Cardiothoracic Surgery, National Heart Institute, Kuala Lumpur, MalaysiaSchool of Pharmaceutical Sciences, Universiti Sains Malaysia, Penang, MalaysiaSchool of Medicine and Health Sciences, Monash University Malaysia, Subang Jaya, MalaysiaBackground: Atrial fibrillation (AF) is common after cardiac surgery and has been associated with poor outcome and increased resource utilization. The main objective of this study is to determine the incidence of POAF in Malaysia and identify the predictors of developing POAF. The secondary outcome of this study would be to investigate the difference in mortality and morbidity rates and the duration of intensive care unit (ICU), high dependency unit (HDU) and hospital stay between the two. Methods: This is a retrospective single-center, cross sectional study conducted at the National Heart Institute, Malaysia. Medical records of 637 who underwent coronary artery bypass grafting (CABG) surgery in 2015 were accrued. Pre-operative, operative and post-operative information were subsequently collected on a pre-formulated data collection sheet. Data were then analyzed using IBM SPSS v23. Results: The incidence of POAF in our study stands at 28.7% with a mean onset of 45±33 hours post operatively. Variables with independent association with POAF include advancing age, Indian population, history of chronic kidney disease, left ventricular ejection fraction and beta-blocker treatment. The mortality rate is significantly higher statistically (p < 0.05), and similarly the incidence of stroke. The incidence of other post-operative complications was also significantly higher statistically. The duration of ICU, HDU and hospital stays were statistically longer (p < 0.001) with higher rates of ICU readmissions and reintubations seen. Conclusion: We conclude that the incidence of POAF in Malaysia is comparable to the figures in Western countries, making POAF one of the most commonly encountered condition after CABG with similar higher rates of mortality, poor outcomes and longer duration of stay, and therefore increased cost of care. Strategies to reduce the incidence of AF after cardiac surgery should favorably affect surgical outcomes and reduce utilization of resources and thus lower cost of care.https://f1000research.com/articles/7-164/v2Arrhythmias, Electrophysiology & PacingCOPD & Allied Disorders |
| spellingShingle | Ahmad Farouk Musa Chou Zhao Quan Low Zheng Xin Trived Soni Jeswant Dillon Yuen Kah Hay Rusli Bin Nordin A retrospective study on atrial fibrillation after coronary artery bypass grafting surgery at The National Heart Institute, Kuala Lumpur [version 2; referees: 2 approved] F1000Research Arrhythmias, Electrophysiology & Pacing COPD & Allied Disorders |
| title | A retrospective study on atrial fibrillation after coronary artery bypass grafting surgery at The National Heart Institute, Kuala Lumpur [version 2; referees: 2 approved] |
| title_full | A retrospective study on atrial fibrillation after coronary artery bypass grafting surgery at The National Heart Institute, Kuala Lumpur [version 2; referees: 2 approved] |
| title_fullStr | A retrospective study on atrial fibrillation after coronary artery bypass grafting surgery at The National Heart Institute, Kuala Lumpur [version 2; referees: 2 approved] |
| title_full_unstemmed | A retrospective study on atrial fibrillation after coronary artery bypass grafting surgery at The National Heart Institute, Kuala Lumpur [version 2; referees: 2 approved] |
| title_short | A retrospective study on atrial fibrillation after coronary artery bypass grafting surgery at The National Heart Institute, Kuala Lumpur [version 2; referees: 2 approved] |
| title_sort | retrospective study on atrial fibrillation after coronary artery bypass grafting surgery at the national heart institute kuala lumpur version 2 referees 2 approved |
| topic | Arrhythmias, Electrophysiology & Pacing COPD & Allied Disorders |
| url | https://f1000research.com/articles/7-164/v2 |
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