Internalization of Polymeric Bacterial Peptidoglycan Occurs through Either Actin or Dynamin Dependent Pathways

Internalization of Polymeric Bacterial Peptidoglycan Occurs through Either Actin or Dynamin Dependent Pathways

Peptidoglycan (PGN), a polymeric glycan macromolecule, is a major constituent of the bacterial cell wall and a conserved pathogen-associated molecular pattern (PAMP) that triggers immune responses through cytosolic sensors. Immune cells encounter both PGN polymers and hydrolyzed muropeptides during...

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Bibliographic Details
Main Authors: Narcis I. Popescu, Jackie Cochran, Elizabeth Duggan, Jędrzej Kluza, Robert Silasi, Kenneth Mark Coggeshall
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Microorganisms
Subjects:
peptidoglycan
bacteria
monocytes
internalization
CIE
Online Access:https://www.mdpi.com/2076-2607/10/3/552

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