Wild at heart: 34-year-old male with new onset dyspnea, heart failure and history of amphetamine use; a case report
Abstract Background Spontaneous coronary artery dissection (SCAD) is a rather rare cause of acute coronary syndrome with a preponderance for young female patients. Amphetamines are now the second most widely used substance drugs in the world and they are associated with a myriad of cardiac diseases...
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| Format: | Article |
| Language: | English |
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SpringerOpen
2019-10-01
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| Series: | The Egyptian Heart Journal |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s43044-019-0026-y |
| _version_ | 1818257310646009856 |
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| author | Hossein Navid Hamidreza Soleimani Kaveh Hosseini |
| author_facet | Hossein Navid Hamidreza Soleimani Kaveh Hosseini |
| author_sort | Hossein Navid |
| collection | DOAJ |
| description | Abstract Background Spontaneous coronary artery dissection (SCAD) is a rather rare cause of acute coronary syndrome with a preponderance for young female patients. Amphetamines are now the second most widely used substance drugs in the world and they are associated with a myriad of cardiac diseases including cardiomyopathies and SCADs. There is much uncertainty regarding the best treatment strategy in such cases and decision-making remains mostly individualized and based on expert opinions. Case presentation A 34-year-old male with an unremarkable past medical history presented to a cardiologist with prominent dyspnea and orthopnea. He reported occasional methamphetamine use from 3 years before the presentation. An echocardiogram showed an enlarged left ventricle and severe systolic dysfunction with an ejection fraction of 10–15%. Coronary angiography revealed multiple linear dissections in both left anterior descending coronary artery (LAD) and left circumflex coronary artery (LCX). The patient’s right coronary artery (RCA) showed occlusion in the proximal segment. The patient was diagnosed with amphetamine-induced spontaneous coronary artery dissection and resultant ischemic cardiomyopathy. After thorough evaluation, medical treatment ensued. Conclusions Methamphetamine abusers have a 3.7 fold risk of developing some form of a cardiomyopathy in comparison to individuals without amphetamine abuse. Coronary artery dissection and increased thrombus burden are some of the mechanisms responsible for ischemic cardiomyopathy in these groups of patients. |
| first_indexed | 2024-12-12T17:41:37Z |
| format | Article |
| id | doaj.art-0f63bf42a4e34cc9a084246a69bae2c0 |
| institution | Directory Open Access Journal |
| issn | 2090-911X |
| language | English |
| last_indexed | 2024-12-12T17:41:37Z |
| publishDate | 2019-10-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | The Egyptian Heart Journal |
| spelling | doaj.art-0f63bf42a4e34cc9a084246a69bae2c02022-12-22T00:17:03ZengSpringerOpenThe Egyptian Heart Journal2090-911X2019-10-017111510.1186/s43044-019-0026-yWild at heart: 34-year-old male with new onset dyspnea, heart failure and history of amphetamine use; a case reportHossein Navid0Hamidreza Soleimani1Kaveh Hosseini2Department of Heart Failure and Heart Transplantation, Tehran Heart Center, Tehran University of Medical SciencesTehran Heart Center, Tehran University of Medical SciencesTehran Heart Center, Tehran University of Medical SciencesAbstract Background Spontaneous coronary artery dissection (SCAD) is a rather rare cause of acute coronary syndrome with a preponderance for young female patients. Amphetamines are now the second most widely used substance drugs in the world and they are associated with a myriad of cardiac diseases including cardiomyopathies and SCADs. There is much uncertainty regarding the best treatment strategy in such cases and decision-making remains mostly individualized and based on expert opinions. Case presentation A 34-year-old male with an unremarkable past medical history presented to a cardiologist with prominent dyspnea and orthopnea. He reported occasional methamphetamine use from 3 years before the presentation. An echocardiogram showed an enlarged left ventricle and severe systolic dysfunction with an ejection fraction of 10–15%. Coronary angiography revealed multiple linear dissections in both left anterior descending coronary artery (LAD) and left circumflex coronary artery (LCX). The patient’s right coronary artery (RCA) showed occlusion in the proximal segment. The patient was diagnosed with amphetamine-induced spontaneous coronary artery dissection and resultant ischemic cardiomyopathy. After thorough evaluation, medical treatment ensued. Conclusions Methamphetamine abusers have a 3.7 fold risk of developing some form of a cardiomyopathy in comparison to individuals without amphetamine abuse. Coronary artery dissection and increased thrombus burden are some of the mechanisms responsible for ischemic cardiomyopathy in these groups of patients.http://link.springer.com/article/10.1186/s43044-019-0026-ySpontaneous coronary artery dissectionIschemic cardiomyopathyMethamphetamine abuse |
| spellingShingle | Hossein Navid Hamidreza Soleimani Kaveh Hosseini Wild at heart: 34-year-old male with new onset dyspnea, heart failure and history of amphetamine use; a case report The Egyptian Heart Journal Spontaneous coronary artery dissection Ischemic cardiomyopathy Methamphetamine abuse |
| title | Wild at heart: 34-year-old male with new onset dyspnea, heart failure and history of amphetamine use; a case report |
| title_full | Wild at heart: 34-year-old male with new onset dyspnea, heart failure and history of amphetamine use; a case report |
| title_fullStr | Wild at heart: 34-year-old male with new onset dyspnea, heart failure and history of amphetamine use; a case report |
| title_full_unstemmed | Wild at heart: 34-year-old male with new onset dyspnea, heart failure and history of amphetamine use; a case report |
| title_short | Wild at heart: 34-year-old male with new onset dyspnea, heart failure and history of amphetamine use; a case report |
| title_sort | wild at heart 34 year old male with new onset dyspnea heart failure and history of amphetamine use a case report |
| topic | Spontaneous coronary artery dissection Ischemic cardiomyopathy Methamphetamine abuse |
| url | http://link.springer.com/article/10.1186/s43044-019-0026-y |
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