Experiences in implementing immunopsychiatry in real life
Immunological mechanisms, both alone and in combination, are associated with a broad range of psychiatric disorders encompassing autoimmune, autoinflammatory disorders but also genetic, metabolic, or other immunological disorders. Early treatment improves the outcome for autoimmune disorders, but ea...
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Format: | Article |
Language: | English |
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Elsevier
2023-07-01
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Series: | Journal of Affective Disorders Reports |
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Online Access: | http://www.sciencedirect.com/science/article/pii/S2666915323001361 |
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author | Janet L. Cunningham Gunnel Nordmark David Fällmar Simon Cervenka Maike Gallwitz Roland Säll Peter T. Schmidt Johan Rönnelid Barbro Persson Andreas Kindmark Joachim Burman |
author_facet | Janet L. Cunningham Gunnel Nordmark David Fällmar Simon Cervenka Maike Gallwitz Roland Säll Peter T. Schmidt Johan Rönnelid Barbro Persson Andreas Kindmark Joachim Burman |
author_sort | Janet L. Cunningham |
collection | DOAJ |
description | Immunological mechanisms, both alone and in combination, are associated with a broad range of psychiatric disorders encompassing autoimmune, autoinflammatory disorders but also genetic, metabolic, or other immunological disorders. Early treatment improves the outcome for autoimmune disorders, but early diagnosis is more difficult when isolated psychiatric symptoms are manifestations of autoimmunity. Treatment of these cases must encompass integrated models of disease, as both systemic autoimmunity and psychological processes influence mental health. Several challenges need to be overcome to efficiently merge psychiatric and somatic disease paradigms and medical care ranging from language and conceptual barriers to organizational barriers. Since 2015, the Immunopsychiatry team at Uppsala University has developed a collaborative multidisciplinary approach to improve and integrate care for patients with moderate to severe psychiatric disorders. Based on this experience, we have outlined the obstacles to be overcome in taking steps forward to achieve the long-term goal of understanding and early detection and identification of treatable immunological conditions within the psychiatric patient population; the described framework of evaluations and work-flow may serve as a model for other centers. |
first_indexed | 2024-03-13T05:00:21Z |
format | Article |
id | doaj.art-0f642af304b643f49e7b07a8f774e76c |
institution | Directory Open Access Journal |
issn | 2666-9153 |
language | English |
last_indexed | 2024-03-13T05:00:21Z |
publishDate | 2023-07-01 |
publisher | Elsevier |
record_format | Article |
series | Journal of Affective Disorders Reports |
spelling | doaj.art-0f642af304b643f49e7b07a8f774e76c2023-06-17T05:21:32ZengElsevierJournal of Affective Disorders Reports2666-91532023-07-0113100597Experiences in implementing immunopsychiatry in real lifeJanet L. Cunningham0Gunnel Nordmark1David Fällmar2Simon Cervenka3Maike Gallwitz4Roland Säll5Peter T. Schmidt6Johan Rönnelid7Barbro Persson8Andreas Kindmark9Joachim Burman10Department of Medical Sciences, Psychiatry, Uppsala University, Uppsala, Sweden; Corresponding author.Department of Medical Sciences, Rheumatology, Uppsala University, Uppsala, SwedenDepartment of Surgical Sciences, Neuroradiology, Uppsala University, Uppsala, SwedenDepartment of Medical Sciences, Psychiatry, Uppsala University, Uppsala, SwedenDepartment of Medical Sciences, Psychiatry, Uppsala University, Uppsala, SwedenDepartment of Medical Sciences, Psychiatry, Uppsala University, Uppsala, SwedenDepartment of Medical Sciences, Gastroenterology and Hepatology, Uppsala University, Uppsala, SwedenDepartment of Immunology, Genetics and Pathology, Uppsala University, Uppsala, SwedenDepartment of Immunology, Genetics and Pathology, Uppsala University, Uppsala, SwedenDepartment of Medical Sciences, Endocrinology and Mineral Metabolism, Uppsala University, Uppsala, SwedenDeptartment of Medical Sciences, Neurology, Uppsala University, Uppsala, SwedenImmunological mechanisms, both alone and in combination, are associated with a broad range of psychiatric disorders encompassing autoimmune, autoinflammatory disorders but also genetic, metabolic, or other immunological disorders. Early treatment improves the outcome for autoimmune disorders, but early diagnosis is more difficult when isolated psychiatric symptoms are manifestations of autoimmunity. Treatment of these cases must encompass integrated models of disease, as both systemic autoimmunity and psychological processes influence mental health. Several challenges need to be overcome to efficiently merge psychiatric and somatic disease paradigms and medical care ranging from language and conceptual barriers to organizational barriers. Since 2015, the Immunopsychiatry team at Uppsala University has developed a collaborative multidisciplinary approach to improve and integrate care for patients with moderate to severe psychiatric disorders. Based on this experience, we have outlined the obstacles to be overcome in taking steps forward to achieve the long-term goal of understanding and early detection and identification of treatable immunological conditions within the psychiatric patient population; the described framework of evaluations and work-flow may serve as a model for other centers.http://www.sciencedirect.com/science/article/pii/S2666915323001361Precision medicinePsychiatryImmunopsychiatryAutoimmunityLimbic encephalitisCSF |
spellingShingle | Janet L. Cunningham Gunnel Nordmark David Fällmar Simon Cervenka Maike Gallwitz Roland Säll Peter T. Schmidt Johan Rönnelid Barbro Persson Andreas Kindmark Joachim Burman Experiences in implementing immunopsychiatry in real life Journal of Affective Disorders Reports Precision medicine Psychiatry Immunopsychiatry Autoimmunity Limbic encephalitis CSF |
title | Experiences in implementing immunopsychiatry in real life |
title_full | Experiences in implementing immunopsychiatry in real life |
title_fullStr | Experiences in implementing immunopsychiatry in real life |
title_full_unstemmed | Experiences in implementing immunopsychiatry in real life |
title_short | Experiences in implementing immunopsychiatry in real life |
title_sort | experiences in implementing immunopsychiatry in real life |
topic | Precision medicine Psychiatry Immunopsychiatry Autoimmunity Limbic encephalitis CSF |
url | http://www.sciencedirect.com/science/article/pii/S2666915323001361 |
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