Experiences in implementing immunopsychiatry in real life

Immunological mechanisms, both alone and in combination, are associated with a broad range of psychiatric disorders encompassing autoimmune, autoinflammatory disorders but also genetic, metabolic, or other immunological disorders. Early treatment improves the outcome for autoimmune disorders, but ea...

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Main Authors: Janet L. Cunningham, Gunnel Nordmark, David Fällmar, Simon Cervenka, Maike Gallwitz, Roland Säll, Peter T. Schmidt, Johan Rönnelid, Barbro Persson, Andreas Kindmark, Joachim Burman
Format: Article
Language:English
Published: Elsevier 2023-07-01
Series:Journal of Affective Disorders Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666915323001361
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author Janet L. Cunningham
Gunnel Nordmark
David Fällmar
Simon Cervenka
Maike Gallwitz
Roland Säll
Peter T. Schmidt
Johan Rönnelid
Barbro Persson
Andreas Kindmark
Joachim Burman
author_facet Janet L. Cunningham
Gunnel Nordmark
David Fällmar
Simon Cervenka
Maike Gallwitz
Roland Säll
Peter T. Schmidt
Johan Rönnelid
Barbro Persson
Andreas Kindmark
Joachim Burman
author_sort Janet L. Cunningham
collection DOAJ
description Immunological mechanisms, both alone and in combination, are associated with a broad range of psychiatric disorders encompassing autoimmune, autoinflammatory disorders but also genetic, metabolic, or other immunological disorders. Early treatment improves the outcome for autoimmune disorders, but early diagnosis is more difficult when isolated psychiatric symptoms are manifestations of autoimmunity. Treatment of these cases must encompass integrated models of disease, as both systemic autoimmunity and psychological processes influence mental health. Several challenges need to be overcome to efficiently merge psychiatric and somatic disease paradigms and medical care ranging from language and conceptual barriers to organizational barriers. Since 2015, the Immunopsychiatry team at Uppsala University has developed a collaborative multidisciplinary approach to improve and integrate care for patients with moderate to severe psychiatric disorders. Based on this experience, we have outlined the obstacles to be overcome in taking steps forward to achieve the long-term goal of understanding and early detection and identification of treatable immunological conditions within the psychiatric patient population; the described framework of evaluations and work-flow may serve as a model for other centers.
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spelling doaj.art-0f642af304b643f49e7b07a8f774e76c2023-06-17T05:21:32ZengElsevierJournal of Affective Disorders Reports2666-91532023-07-0113100597Experiences in implementing immunopsychiatry in real lifeJanet L. Cunningham0Gunnel Nordmark1David Fällmar2Simon Cervenka3Maike Gallwitz4Roland Säll5Peter T. Schmidt6Johan Rönnelid7Barbro Persson8Andreas Kindmark9Joachim Burman10Department of Medical Sciences, Psychiatry, Uppsala University, Uppsala, Sweden; Corresponding author.Department of Medical Sciences, Rheumatology, Uppsala University, Uppsala, SwedenDepartment of Surgical Sciences, Neuroradiology, Uppsala University, Uppsala, SwedenDepartment of Medical Sciences, Psychiatry, Uppsala University, Uppsala, SwedenDepartment of Medical Sciences, Psychiatry, Uppsala University, Uppsala, SwedenDepartment of Medical Sciences, Psychiatry, Uppsala University, Uppsala, SwedenDepartment of Medical Sciences, Gastroenterology and Hepatology, Uppsala University, Uppsala, SwedenDepartment of Immunology, Genetics and Pathology, Uppsala University, Uppsala, SwedenDepartment of Immunology, Genetics and Pathology, Uppsala University, Uppsala, SwedenDepartment of Medical Sciences, Endocrinology and Mineral Metabolism, Uppsala University, Uppsala, SwedenDeptartment of Medical Sciences, Neurology, Uppsala University, Uppsala, SwedenImmunological mechanisms, both alone and in combination, are associated with a broad range of psychiatric disorders encompassing autoimmune, autoinflammatory disorders but also genetic, metabolic, or other immunological disorders. Early treatment improves the outcome for autoimmune disorders, but early diagnosis is more difficult when isolated psychiatric symptoms are manifestations of autoimmunity. Treatment of these cases must encompass integrated models of disease, as both systemic autoimmunity and psychological processes influence mental health. Several challenges need to be overcome to efficiently merge psychiatric and somatic disease paradigms and medical care ranging from language and conceptual barriers to organizational barriers. Since 2015, the Immunopsychiatry team at Uppsala University has developed a collaborative multidisciplinary approach to improve and integrate care for patients with moderate to severe psychiatric disorders. Based on this experience, we have outlined the obstacles to be overcome in taking steps forward to achieve the long-term goal of understanding and early detection and identification of treatable immunological conditions within the psychiatric patient population; the described framework of evaluations and work-flow may serve as a model for other centers.http://www.sciencedirect.com/science/article/pii/S2666915323001361Precision medicinePsychiatryImmunopsychiatryAutoimmunityLimbic encephalitisCSF
spellingShingle Janet L. Cunningham
Gunnel Nordmark
David Fällmar
Simon Cervenka
Maike Gallwitz
Roland Säll
Peter T. Schmidt
Johan Rönnelid
Barbro Persson
Andreas Kindmark
Joachim Burman
Experiences in implementing immunopsychiatry in real life
Journal of Affective Disorders Reports
Precision medicine
Psychiatry
Immunopsychiatry
Autoimmunity
Limbic encephalitis
CSF
title Experiences in implementing immunopsychiatry in real life
title_full Experiences in implementing immunopsychiatry in real life
title_fullStr Experiences in implementing immunopsychiatry in real life
title_full_unstemmed Experiences in implementing immunopsychiatry in real life
title_short Experiences in implementing immunopsychiatry in real life
title_sort experiences in implementing immunopsychiatry in real life
topic Precision medicine
Psychiatry
Immunopsychiatry
Autoimmunity
Limbic encephalitis
CSF
url http://www.sciencedirect.com/science/article/pii/S2666915323001361
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