A Pro‐Regenerative Supramolecular Prodrug Protects Against and Repairs Colon Damage in Experimental Colitis

A Pro‐Regenerative Supramolecular Prodrug Protects Against and Repairs Colon Damage in Experimental Colitis

Abstract Structural repair of the intestinal epithelium is strongly correlated with disease remission in inflammatory bowel disease (IBD); however, ulcer healing is not addressed by existing therapies. To address this need, this study reports the use of a small molecule prolyl hydroxylase (PHD) inhi...

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Bibliographic Details
Main Authors: Kelsey G. DeFrates, Elaine Tong, Jing Cheng, Ellen Heber‐Katz, Phillip B. Messersmith
Format: Article
Language:English
Published: Wiley 2024-04-01
Series:Advanced Science
Subjects:
HIF‐1α
inflammatory bowel disease
prolyl hydroxylase inhibitor
regeneration
Online Access:https://doi.org/10.1002/advs.202304716

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