Associations of executive function and age of first use of methamphetamine with methamphetamine relapse
Background and aimsMethamphetamine (MA) is a psychostimulant associated with a high relapse rate among patients with MA use disorder (MUD). Long-term use of MA is associated with mental disorders, executive dysfunction, aggressive behaviors, and impulsivity among patients with MUD. However, identify...
| Main Authors: | , , , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-10-01
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| Series: | Frontiers in Psychiatry |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fpsyt.2022.971825/full |
| _version_ | 1798019537928454144 |
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| author | Lin-Lin Mu Yan Wang Li-Jin Wang Ling-Ling Xia Wei Zhao Pei-Pei Song Jun-Da Li Wen-Juan Wang Lin Zhu Hao-Nan Li Yu-Jing Wang Hua-Jun Tang Lei Zhang Xun Song Wen-Yi Shao Xiao-Chu Zhang Hua-Shan Xu Dong-Liang Jiao |
| author_facet | Lin-Lin Mu Yan Wang Li-Jin Wang Ling-Ling Xia Wei Zhao Pei-Pei Song Jun-Da Li Wen-Juan Wang Lin Zhu Hao-Nan Li Yu-Jing Wang Hua-Jun Tang Lei Zhang Xun Song Wen-Yi Shao Xiao-Chu Zhang Hua-Shan Xu Dong-Liang Jiao |
| author_sort | Lin-Lin Mu |
| collection | DOAJ |
| description | Background and aimsMethamphetamine (MA) is a psychostimulant associated with a high relapse rate among patients with MA use disorder (MUD). Long-term use of MA is associated with mental disorders, executive dysfunction, aggressive behaviors, and impulsivity among patients with MUD. However, identifying which factors may be more closely associated with relapse has not been investigated. Thus, we aimed to investigate the psychological factors and the history of MA use that may influence MA relapse.MethodsThis cross-sectional study included 168 male MUD patients (MUD group) and 65 healthy male residents (control group). Each patient was evaluated with self-report measures of executive dysfunction, psychopathological symptoms, impulsiveness, aggressiveness, and history of MA use. Data were analyzed with t-tests, analyses of variance, and correlation and regression analyses.ResultsThe MUD group reported greater executive dysfunction, psychopathological symptoms, impulsivity, and aggression than the control group. Lower age of first MA use was associated both with having relapsed one or more times and with having relapsed two or more times; greater executive dysfunction was associated only with having relapsed two or more times.ConclusionPatients with MUD reported worse executive function and mental health. Current results also suggest that lower age of first MA use may influence relapse rate in general, while executive dysfunction may influence repeated relapse in particular. The present results add to the literature concerning factors that may increase the risk of relapse in individuals with MUD. |
| first_indexed | 2024-04-11T16:42:17Z |
| format | Article |
| id | doaj.art-0f6b0b9f0170493e91256ffdae698f66 |
| institution | Directory Open Access Journal |
| issn | 1664-0640 |
| language | English |
| last_indexed | 2024-04-11T16:42:17Z |
| publishDate | 2022-10-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Psychiatry |
| spelling | doaj.art-0f6b0b9f0170493e91256ffdae698f662022-12-22T04:13:38ZengFrontiers Media S.A.Frontiers in Psychiatry1664-06402022-10-011310.3389/fpsyt.2022.971825971825Associations of executive function and age of first use of methamphetamine with methamphetamine relapseLin-Lin Mu0Yan Wang1Li-Jin Wang2Ling-Ling Xia3Wei Zhao4Pei-Pei Song5Jun-Da Li6Wen-Juan Wang7Lin Zhu8Hao-Nan Li9Yu-Jing Wang10Hua-Jun Tang11Lei Zhang12Xun Song13Wen-Yi Shao14Xiao-Chu Zhang15Hua-Shan Xu16Dong-Liang Jiao17School of Mental Health, Bengbu Medical College, Bengbu, ChinaSchool of Mental Health, Bengbu Medical College, Bengbu, ChinaSchool of Mental Health, Bengbu Medical College, Bengbu, ChinaSchool of Mental Health, Bengbu Medical College, Bengbu, ChinaSchool of Mental Health, Bengbu Medical College, Bengbu, ChinaSchool of Mental Health, Bengbu Medical College, Bengbu, ChinaSchool of Mental Health, Bengbu Medical College, Bengbu, ChinaSchool of Mental Health, Bengbu Medical College, Bengbu, ChinaSchool of Mental Health, Bengbu Medical College, Bengbu, ChinaSchool of Mental Health, Bengbu Medical College, Bengbu, ChinaSchool of Mental Health, Bengbu Medical College, Bengbu, ChinaCompulsory Isolated Drug Rehabilitation Center, Bengbu, ChinaSchool of Mental Health, Bengbu Medical College, Bengbu, ChinaSchool of Mental Health, Bengbu Medical College, Bengbu, ChinaSchool of Mental Health, Bengbu Medical College, Bengbu, ChinaChinese Academy of Sciences (CAS) Key Laboratory of Brain Function and Disease and School of Life Sciences, University of Science and Technology of China, Hefei, ChinaSchool of Mental Health, Bengbu Medical College, Bengbu, ChinaSchool of Mental Health, Bengbu Medical College, Bengbu, ChinaBackground and aimsMethamphetamine (MA) is a psychostimulant associated with a high relapse rate among patients with MA use disorder (MUD). Long-term use of MA is associated with mental disorders, executive dysfunction, aggressive behaviors, and impulsivity among patients with MUD. However, identifying which factors may be more closely associated with relapse has not been investigated. Thus, we aimed to investigate the psychological factors and the history of MA use that may influence MA relapse.MethodsThis cross-sectional study included 168 male MUD patients (MUD group) and 65 healthy male residents (control group). Each patient was evaluated with self-report measures of executive dysfunction, psychopathological symptoms, impulsiveness, aggressiveness, and history of MA use. Data were analyzed with t-tests, analyses of variance, and correlation and regression analyses.ResultsThe MUD group reported greater executive dysfunction, psychopathological symptoms, impulsivity, and aggression than the control group. Lower age of first MA use was associated both with having relapsed one or more times and with having relapsed two or more times; greater executive dysfunction was associated only with having relapsed two or more times.ConclusionPatients with MUD reported worse executive function and mental health. Current results also suggest that lower age of first MA use may influence relapse rate in general, while executive dysfunction may influence repeated relapse in particular. The present results add to the literature concerning factors that may increase the risk of relapse in individuals with MUD.https://www.frontiersin.org/articles/10.3389/fpsyt.2022.971825/fullmethamphetamine use disorderexecutive functionmental disordersthe age of first userelapse |
| spellingShingle | Lin-Lin Mu Yan Wang Li-Jin Wang Ling-Ling Xia Wei Zhao Pei-Pei Song Jun-Da Li Wen-Juan Wang Lin Zhu Hao-Nan Li Yu-Jing Wang Hua-Jun Tang Lei Zhang Xun Song Wen-Yi Shao Xiao-Chu Zhang Hua-Shan Xu Dong-Liang Jiao Associations of executive function and age of first use of methamphetamine with methamphetamine relapse Frontiers in Psychiatry methamphetamine use disorder executive function mental disorders the age of first use relapse |
| title | Associations of executive function and age of first use of methamphetamine with methamphetamine relapse |
| title_full | Associations of executive function and age of first use of methamphetamine with methamphetamine relapse |
| title_fullStr | Associations of executive function and age of first use of methamphetamine with methamphetamine relapse |
| title_full_unstemmed | Associations of executive function and age of first use of methamphetamine with methamphetamine relapse |
| title_short | Associations of executive function and age of first use of methamphetamine with methamphetamine relapse |
| title_sort | associations of executive function and age of first use of methamphetamine with methamphetamine relapse |
| topic | methamphetamine use disorder executive function mental disorders the age of first use relapse |
| url | https://www.frontiersin.org/articles/10.3389/fpsyt.2022.971825/full |
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